110582-34-8Relevant academic research and scientific papers
Potent Inhibition of Pepsin and Penicillopepsin by Phosphorus-Containing Peptide Analogues
Bartlett, Paul A.,Hanson, John E.,Giannousis, Peter P.
, p. 6268 - 6274 (2007/10/02)
Phosphinic and phosphonic acid peptide derivatives have been evaluated as inhibitors of the aspartic proteases pepsin and penicillopepsin.The most potent of those studied is isovaleryl-Val-Val-LeuP-(O)Phe-Ala-Ala-OMe (4) (LeuP repres
Synthesis of phosphonamides and phosphinamides related to pepstatin
Bartlett, Paul A.,Acher, Francine
, p. 771 - 775 (2007/10/02)
Activation with diphenyl phosphoryl azide (DPPA) and displacement with ammonia constitute a general procedure for conversion of phosphonic and phosphinic acids into their amides.This procedure can be applied to oligopeptide derivatives, unless intramolecu
