88081-77-0

Basic information

• Product Name: (R)-1-PHOSPHONO-3-METHYL-BUTYLAMINE
• Synonyms: (R)-1-PHOSPHONO-3-METHYL-BUTYLAMINE;(R)-1-AMINO(3-METHYLBUTYL)PHOSPHONIC ACID;H-R-LEU(P)-OH
• CAS NO: 88081-77-0
• Molecular Formula: C₅H₁₄NO₃P
• Molecular Weight: 167.14
• Mol File: 88081-77-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-1-PHOSPHONO-3-METHYL-BUTYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-PHOSPHONO-3-METHYL-BUTYLAMINE(88081-77-0)
• EPA Substance Registry System: (R)-1-PHOSPHONO-3-METHYL-BUTYLAMINE(88081-77-0)

Safety Data

• Hazardous Substances Data: 88081-77-0(Hazardous Substances Data)

Usage

Description

(R)-1-PHOSPHONO-3-METHYL-BUTYLAMINE, with the molecular formula C5H15NO3P, is a phosphorus-containing chemical compound. It is recognized for its versatile properties and is commonly utilized in a range of industrial and scientific applications.

Uses

Used in Water Treatment Industry:
(R)-1-PHOSPHONO-3-METHYL-BUTYLAMINE is used as a chelating agent and corrosion inhibitor for its ability to bind with metal ions and prevent corrosion, which is crucial in maintaining the integrity and efficiency of water treatment systems.
Used in Pharmaceutical Synthesis:
In the pharmaceutical sector, (R)-1-PHOSPHONO-3-METHYL-BUTYLAMINE is used as a stabilizer and sequestrant. Its role is to enhance the stability of pharmaceutical compounds during their synthesis, ensuring the production of high-quality and effective drugs.
Used in Biochemical Research:
As a buffering agent in biochemical research, (R)-1-PHOSPHONO-3-METHYL-BUTYLAMINE helps maintain a stable pH environment, which is essential for various biological and chemical reactions to occur efficiently.
Used in Agriculture and Horticulture:
In the agricultural and horticultural sectors, (R)-1-PHOSPHONO-3-METHYL-BUTYLAMINE is used as a plant growth regulator and nutrient uptake enhancer. It contributes to the improved growth and development of crops by optimizing the absorption of essential nutrients.

Upstream product

• 104513-35-1 1-(N-Phenylacetylamino)-3-methylbutylphosphonic acid 
• 328-39-2 LEUCINE 
• 65415-00-1 N-phenylacetyl-D,L-leucine 

Downstream Products

• 437999-42-3 (R)-N-(4-allyloxy-3,5-dichlorobenzoyl)-1-amino-3-methylbutane phosphonic acid 
• 128901-71-3 (S)-2-{(S)-2-[(S)-2-({(R)-1-[(S)-2-((S)-2-Benzyloxycarbonylamino-propionylamino)-propionylamino]-3-methyl-butyl}-methoxy-phosphinoyloxy)-3-phenyl-propionylamino]-propionylamino}-propionic acid methyl ester 
• 128948-76-5 Cbz-Ala-Ala-Leu^P-(O)Phe-Ala-Ala-OMe 
• 128901-58-6 Iva-Val-Val-Leu^P-(O)Phe-Ala-Ala dimethyl ester 
• 128901-50-8 Iva-Val-Val-Leu^P-(O)Phe-Ala-Ala-OMe 
• 128901-57-5 Cbz-Leu^P-(O)Phe-Ala-Ala dimethyl ester 
• 128901-69-9 (S)-2-({(R)-1-[(S)-2-((S)-2-Benzyloxycarbonylamino-propionylamino)-propionylamino]-3-methyl-butyl}-methoxy-phosphinoyloxy)-3-phenyl-propionic acid methyl ester 
• 128901-55-3 Cbz-Ala-Ala-Leu^P-(O)Phe-OMe 
• 128901-70-2 (S)-2-[Methoxy-((R)-3-methyl-1-{(S)-3-methyl-2-[(R)-3-methyl-2-(3-methyl-butyrylamino)-butyrylamino]-butyrylamino}-butyl)-phosphinoyloxy]-3-phenyl-propionic acid methyl ester 
• 128923-36-4 Iva-Val-Val-Leu^P-(O)Phe-OMe 
• 90763-60-3 ((R)-1-Benzyloxycarbonylamino-3-methyl-butyl)-{[(S)-1-(3-methyl-butylcarbamoyl)-ethylcarbamoyl]-methyl}-phosphinic acid methyl ester 
• 110582-34-8 C₂₃H₃₉N₄O₅P 
• 110582-44-0 ((R)-1-Benzyloxycarbonylamino-3-methyl-butyl)-{[(S)-1-(3-methyl-butylcarbamoyl)-ethylcarbamoyl]-methyl}-phosphinic acid 
• 208046-11-1 (S)-2-[((R)-1-Benzyloxycarbonylamino-3-methyl-butyl)-methoxy-phosphinoyloxy]-3-phenyl-propionic acid methyl ester 

Relevant articles and documents

Batch and in-flow kinetic resolution of racemic 1-(N-acylamino)alkylphosphonic and 1-(N-acylamino)alkylphosphinic acids and their esters using immobilized penicillin G acylase

The kinetic resolution of racemic 1-(N-acylamino)alkylphosphonic acids 3 (R3= OH) and their dimethyl esters 1, as well as 1-(N-acylamino)alkylphosphinic acids 4 (R3= H or Ph) using penicillin G acylase (PGA) immobilized on three type

Preparation of optically active 1-aminoalkylphosphonic acids by stereoselective enzymatic hydrolysis of racemic N-acylated 1-aminoalkylphosphonic acids

N-Phenylacetylated derivatives of 1-aminoalkylphosphonic acids were synthesized and high enantioselectivity of their hydrolysis by penicillin acylase (EC 3.5.1.11) was demonstrated. Stereoselective enzymatic hydrolysis of racemic 1-(N-phenylacetylamino) alkylphosphonic acids was used for preparation of enantiomeric 1-aminoalkylphosphonic acids. The kinetic regularities of penicillin acylase catalyzed hydrolysis were established and the biocatalytic process was optimized to increase the optical purity and the yield of the optically active product.