110690-36-3

Basic information

• Product Name: 1-HEXANOL, 2,6-DIAMINO-, (2S)-
• Synonyms: 1-HEXANOL, 2,6-DIAMINO-, (2S)-;(S)-2,6-diaminohexan-1-ol;REF DUPL: L-Lysinol
• CAS NO: 110690-36-3
• Molecular Formula: C₆H₁₆N₂O
• Molecular Weight: 132.2
• Mol File: 110690-36-3.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-HEXANOL, 2,6-DIAMINO-, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-HEXANOL, 2,6-DIAMINO-, (2S)-(110690-36-3)
• EPA Substance Registry System: 1-HEXANOL, 2,6-DIAMINO-, (2S)-(110690-36-3)

Safety Data

• Hazardous Substances Data: 110690-36-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Biochemical Research:
1-HEXANOL, 2,6-DIAMINO-, (2S)is used as a chiral building block for the synthesis of various pharmaceuticals and bioactive compounds. Its unique stereochemistry enables the development of enantiomerically pure compounds, which can exhibit different biological activities and reduce potential side effects.
Used in Metal Complexes:
1-HEXANOL, 2,6-DIAMINO-, (2S)is used as a ligand for metal complexes, providing a platform for the development of new catalysts, sensors, and materials with enhanced properties and applications in various fields.
Used in Antimicrobial Applications:
1-HEXANOL, 2,6-DIAMINO-, (2S)has been studied for its antibacterial and antifungal properties, making it a potential candidate for the development of new antimicrobial agents to combat drug-resistant infections.
Used in Chemical Industry:
1-HEXANOL, 2,6-DIAMINO-, (2S)is used in the chemical industry for the synthesis of various compounds and materials, leveraging its versatile chemical properties and reactivity.

Upstream product

• 7274-88-6 D-lysine hydrochloride 
• 56-87-1 L-lysine 
• 657-27-2 L-Lysine hydrochloride 
• 122477-82-1 tert-butyl-N-[(5S)-5-(benzyloxycarbonylamino)-6-hydroxyhexyl]carbamate 

Downstream Products

• 137649-64-0 N,N-bis-Cbz-L-lysinol 
• 137649-82-2 {4-[(4S,5R,4'S,5'R)-4'-(4-Benzyloxycarbonylamino-butyl)-2,2'-dioxo-3,3'-bis-((R)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionyl)-[5,5']bioxazolidinyl-4-yl]-butyl}-carbamic acid benzyl ester 
• 137649-70-8 (5S,6R,7R,8S)-1,5,8,12-Tetrakis-6,7-dodecanediol 
• 138207-66-6 N^α,N^ε-bis(benzyloxycarbonyl)-D-lysinal 

Relevant articles and documents

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LYSINE AND PROLINE BASED FLAME RETARDANTS

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Lysinol: A renewably resourced alternative to petrochemical polyamines and aminoalcohols

This paper reports the preparation of lysinol (2,6-diamino-1-hexanol) by the hydrogenation of lysine and an example of its use as a replacement for petrochemical-derived amines. Lysine is presently manufactured by fermentation of sugars and other carbon sources at scale exceeding 109 kg per year. Therefore, lysinol is potentially a renewable, platform aminoalcohol of previously unrecognized potential. Lysine hydrogenation proceeds under relatively modest conditions with Ru/C catalyst in water (100-150 °C, 48-70 bar, pH 1.5-2) to give lysinol in good yield (100% conversion, >90% selectivity; 50-70% isolated yield after purification by distillation). The impact of the various reaction parameters on conversion and selectivity are presented and discussed. Lysine hydrogenation at higher temperatures provides a pathway to piperidines and other products via further reduction and elimination of lysinol. The feasibility of lysinol synthesis from commodity, animal feed-grade lysine sources is presented as well. An example of the potential utility of lysinol is demonstrated by its use as a diamine curing agent with a standard epoxy resin. The properties of the resulting thermoset are contrasted with that obtained with a typical petrochemical amine used in this application (diethylenetriamine, DETA). This journal is