110723-51-8

Basic information

• Product Name: N-tert-butyl-4-chloro-3-nitrobenzamide
• Synonyms: N-tert-butyl-4-chloro-3-nitrobenzamide
• CAS NO: 110723-51-8
• Molecular Formula: C₁₁H₁₃ClN₂O₃
• Molecular Weight: 256.68552
• Mol File: 110723-51-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-tert-butyl-4-chloro-3-nitrobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-tert-butyl-4-chloro-3-nitrobenzamide(110723-51-8)
• EPA Substance Registry System: N-tert-butyl-4-chloro-3-nitrobenzamide(110723-51-8)

Safety Data

• Hazardous Substances Data: 110723-51-8(Hazardous Substances Data)

Upstream product

• 119072-55-8 tert-butylisonitrile 
• 41252-95-3 1-chloro-4-iodo-2-nitrobenzene 
• 75-64-9 tert-butylamine 
• 96-99-1 4-chloro-3-nitrobenzoate 
• 38818-50-7 4-chloro-3-nitro-benzoyl chloride 

Downstream Products

• 1169483-76-4 4-(4-bromo-2-chloro-5-fluoro-phenoxy)-N-tert-butyl-3-nitro-benzamide 
• 1169483-46-8 2-(4-(4-(tert-butylcarbamoyl)-2-nitrophenoxy)-2,5-difluorophenyl)acetic acid 
• 1274666-43-1 C₁₉H₁₉ClN₂O₆ 
• 1274666-46-4 C₁₉H₁₈ClFN₂O₆ 

Relevant articles and documents

Preparation of active esters on solid support for aqueous-phase peptide couplings

TentaGel supported active esters analogous to those prepared from solution-phase reagents such as 1-hydroxybenzotriazole, N-hydroxysuccinimide, and pentafluorophenol were prepared and examined for their ability to effect aqueous-phase peptide couplings. HOBt esters showed high hydrolysis rates, relative to peptide coupling, while active esters derived from 4-hydroxy-2,3,5,6-tetrafluorobenzoic acid produced mainly dipeptide coupling products when treated with amino acids in water.

Discovery of AMG 853, a CRTH2 and DP dual antagonist

Prostaglandin D2 (PGD2) plays a key role in mediating allergic reactions seen in asthma, allergic rhinitis, and atopic dermatitis. PGD2 exerts its activity through two G protein-coupled receptors (GPCRs), prostanoid D rece