111015-74-8

Basic information

• Product Name: C₂₁H₂₂O₈
• CAS NO: 111015-74-8
• Molecular Weight: 402.401
• Mol File: 111015-74-8.mol

Chemical Properties

• CAS DataBase Reference: C₂₁H₂₂O₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₂₂O₈(111015-74-8)
• EPA Substance Registry System: C₂₁H₂₂O₈(111015-74-8)

Safety Data

• Hazardous Substances Data: 111015-74-8(Hazardous Substances Data)

Upstream product

• 138223-77-5 C₂₇H₃₀O₈ 
• 17793-95-2 cis-1,2-dihydrocatechol 
• 111015-72-6 (1α,2β,3β,6β)-6-methoxy-4-cyclohexene-1,2,3-triol 2,3-dibenzoate 
• 98-88-4 benzoyl chloride 
• 111015-71-5 (1α,2α,5β,6Sb)-5,6-epoxy-3-cyclohexene-1,2-diol dibenzoate 
• 86504-06-5 cis-3,5-cyclohexadiene-1,2-diol dibenzoate 

Downstream Products

• 484-68-4 4-O-methyl-myo-inositol 

Relevant articles and documents

A concise synthesis of (-)-conduritol F from L-quebrachitol via AlCl3-n-Bu4NI mediated demethylation

(-)-Conduritol F was prepared starting from naturally occurring cyclitol, L-quebrachitol, in 5 steps via AlCl3-Bu4NI mediated chemoselective demethylation of the methyl ether. A preparation of (+)-conduritol B was also described.

Mikrobial Oxidation in Synthesis: Preparation of (+)- and (-)-Pinitol from Benzene

Microbial oxidation with Pseudomonas putida of benzene affords cis-1,2-dihydroxycyclohexa-3,5-diene (2) which may be converted in five steps and 49percent overall yield to (+/-)-pinitol.Resolution of an intermediate alcohol (6) with menthoxyacetyl chloride provides optically pure materials which may be independently transformed to (+)- or (-)-pinitol.Demethylation conditions for pinitol together with further reactions of (2) and related compounds were investigated.

MICROBIAL OXIDATION IN SYNTHESIS: A SIX STEP PREPARATION OF (+/-)-PINITOL FROM BENZENE

Synthesis of (+/-)-pinitol in 35percent overall yield from benzene has been achieved where the key step involved microbial oxidation of benzene to cis-1,2-dihydroxycyclohexa-3,5-diene.