1112-36-3

Usage

Physical State

Colorless liquid

Main Uses

a. Production of fluorinated organic compounds
b. Refrigerant
c. Intermediate in the synthesis of pharmaceuticals and agrochemicals

Hazardous Properties

a. Harmful if swallowed
b. Harmful if inhaled
c. Harmful if absorbed through the skin

Health Effects

a. Irritation to the respiratory system
b. Irritation to the skin
c. Irritation to the eyes

Environmental Impact

Hazardous to aquatic organisms, can persist in the environment

Safety Measures

Handle with care and follow proper safety measures when working with this chemical

Upstream product

• 13116-53-5 1,2,2,3-tetrachloropropane 
• 6186-91-0 3-chloro-2-fluoropropene 
• 33420-47-2 3-chloro-2,2-difluoro-1-propanol 
• 463-49-0 1,2-propanediene 
• 534-07-6 1,3-Dichloroacetone 
• 71-43-2 benzene 
• 7664-39-3 hydrogen fluoride 
• 78-88-6 2,3-Dichloroprop-1-ene 

Downstream Products

• 677-54-3 1,1,1,3-tetrachloro-2,2-difluoropropane 
• 3182-26-1 1,1,1,3,3,3-hexachloro-2,2-difluoro-propane 
• 813-75-2 1,3-difluoro-2,2-difluoropropane 
• 56758-54-4 1,2,2-trifluoro-3-chloropropane 

Relevant academic research and scientific papers

A New Preparative Method for 1-Chloro-2,2,3-trifluoropropane (HCFC-253ca)

Allene was both fluorinated and chlorofluorinated with chlorine monofluoride serving as a well-known chlorofluorinating and chlorinating reagent. 1-Chloro-2,2,3-trifluoropropane was obtained as a major product in the presence of cesium fluoride.

REACTIONS OF HALOGEN FLUORIDES. VII. FLUORINATION OF UNSATURATED COMPOUNDS WITH BROMINE TRIFLUORIDE AND AN EQUIMOLAR MIXTURE OF BROMINE TRIFLUORIDE WITH MOLECULAR BROMINE

The reactions of bromine trifluoride and an equimolar mixture of bromine trifluoride and bromine with halogen-substituted alkenes and methyl α-substituted acrylates were investigated.With sufficient dilution of the substrate by Freon 113 (20-25:1) it is possible to obtain the bromofluoro and difluoro adducts with good yiels.The best results (overall yields of fluorination products 80-83percent) were obtained with alkenes containing a halogen at the multiple bond; in the case of more reactive substrates the reaction becomes nonpreparative.The bromofluorination of E- and Z-1,2-dichloroethylenes and E- and Z-1,3-dichloropropenes with pure bromine trifluoride is antistereospecific.The bromofluorination of E- and Z-1,2-dichloroethylenes by the BrF3-Br2 system gives a mixture of diastereomeric bromofluoro adducts as a result of isomerization of the initial olefins in the presence of the bromine.The formation of the difluorides of the halogenated olefins is nonstereospecific and is accompanied by migration of the halogens.