111669-24-0

Basic information

• Product Name: 3-(Ethylamino)-2-(1-piperazinyl)pyridine
• Synonyms: 3-(Ethylamino)-2-(1-piperazinyl)pyridine;N-Ethyl-2-(piperazin-1-yl)pyridin-3-aMine
• CAS NO: 111669-24-0
• Molecular Formula: C₁₁H₁₈N₄
• Molecular Weight: 206.29
• Product Categories: pharmacetical
• Mol File: 111669-24-0.mol

Chemical Properties

• Boiling Point: 387.7°Cat760mmHg
• Flash Point: 188.3°C
• Appearance: /
• Density: 1.103g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.579
• CAS DataBase Reference: 3-(Ethylamino)-2-(1-piperazinyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Ethylamino)-2-(1-piperazinyl)pyridine(111669-24-0)
• EPA Substance Registry System: 3-(Ethylamino)-2-(1-piperazinyl)pyridine(111669-24-0)

Safety Data

• Hazardous Substances Data: 111669-24-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H18N4/c1-2-13-10-4-3-5-14-11(10)15-8-6-12-7-9-15/h3-5,12-13H,2,6-9H2,1H3

Upstream product

• 111669-26-2 4-(3-ethylaminopyridin-2-yl)piperazine-1-carboxylic acid tert-butyl ester 
• 5470-18-8 2-Chloro-3-nitropyridine 
• 87394-62-5 1-(3-amino-pyridin-2-yl)-piperazine 
• 34803-66-2 1-(2-pyridyl)piperazine 
• 111669-25-1 1-[1,1-dimethylethoxycarbonyl]-4-[3-amino-2-pyridinyl]piperazine 
• 87394-48-7 1-(3-nitro-2-pyridinyl)piperazine 

Downstream Products

• 136816-72-3 1-(indolyl-2-carbonyl)-4-<3-(ethylamino)-2-pyridyl>piperazine 
• 136816-67-6 1-[4-Methoxy-3,5-dimethylbenzyl]-4-[3-(ethylamino)-2-pyridinyl]piperazine 
• 136816-78-9 1-(indolyl-2-carbonyl)-4-<3-(diethylamino)-2-pyridyl>piperazine 
• 153473-54-2 1-(indolyl-2-carbonyl)-4<3-(N-ethylacetamido)-2-pyridyl>piperazine 

Relevant articles and documents

PIPERAZINE AND PIPERIDINE MGLUR5 POTENTIATORS

Compounds of Formula I or pharmaceutically acceptable salts or solvates thereof, wherein A, B, D, Ar1, Ar2, R2, R3, R4, a, m and n are defined in the specification, methods for the use thereof, processes for making and pharmaceutical compositions containing the same.

The production of 3-alkylamino-2-piperazinylpyridines

The invention is a process to produce 3-alkylamino-2-piperazinylpyridines (III), where R3is -CH2-CH3or -CH(CH3)2, and a process to purify them. The 3-alkylamino-2-piperazinylpyridines (III) are used in the production of known compounds useful for treating individuals who are HIV positive.

Amines useful in producing pharmaceutically active CNS compounds

Disclosed are Δ9(11) -steroids (VI) and amino substituted steroids (XI) which contain an amino group attached to the terminal carbon atom of the C17 -side chain, more particularly amino steroids (Ia and Ib), aromatic steroids (II), Δ16 -steroids (IIIa and IIIb), reduced A-ring steroids (IV), Δ17(20) -steroids (Va and Vb) and Δ9(11) -steroids (VI) which are useful as pharmaceutical agents for treating a number of conditions.

Pharmaceutically active amines

The aromatic amines (I), alkyl amines (II), bicyclic amines (III). STR1 cycloalkyl amines (IV), aromatic bicyclic amines (V), hydroquinone amines (VI), quinone amines (VII), amino-ethers (VIII) and bicyclic amino ethers (IX) are useful as pharmaceutical agents for treating a number of conditions including spinal trauma, mild and/or moderate to severe head injury, etc. Also disclosed is a method of treatment using the 3,4-dihydrobenzopyrans (XI).

Amines useful in producing pharmaceutically active CNS compounds

Disclosed are Δ9(11) -steroids (VI) and amino substituted steroids (XI) which contain an amino group attached to the terminal carbon atom of the C17 -side chain, more particularly amino steroids (Ia and Ib), aromatic steroids (II), Δ16 -steroids (IIIa and IIIb), reduced A-ring steroids (IV), Δ17(20) -steroids (Va and Vb) and Δ9(11) -steroids (VI) which are useful as pharmaceutical agents for treating a number of conditions.

Amino-9,10-secosteroids useful for treating head injury, spinal cord trauma or stroke

The amino-9,10-secosteroids STR1 of the present invention contain an amino group attached to the terminal carbon atom of the C17 -side chain and are useful as pharmaceutical agents for treating a number of conditions including spinal trauma, mild and/or moderate to severe head injury, etc.

Novel 21-Aminosteroids That Inhibit Iron-Dependent Lipid Peroxidation and Protect against Central Nervous System Trauma

A novel class of 21-aminosteroids has been developed.Compounds within this series are potent inhibitors of iron-dependent lipid peroxidation in rat brain homogenates with IC50's as low as 3 μM.Furthermore, selected members enhance early neurolo

C20 Through C26 amino steroids

Disclosed are Δ9 (11)-steroids (VI) and amino substituted steroids of formula (XI) which contain an amino group attached to the terminal carbon atom of the C17-side chain, more particularly amino steroids (Ia and Ib), aromatic steroids (II), Δ16 (11)-steroids (IIIa and IIIb), reduced A-ring steroids (IV), Δ17 (20)-steroids (Va and Vb) and Δ9 (11)-steroids (VI) which are useful as pharmaceutical agents for treating a number of conditions.