87394-62-5

Basic information

• Product Name: 3-Pyridinamine,2-(1-piperazinyl)-(9CI)
• Synonyms: 3-Pyridinamine,2-(1-piperazinyl)-(9CI);2-Piperazin-1-yl-pyridin-3-ylamine
• CAS NO: 87394-62-5
• Molecular Formula: C9 H14 N4
• Molecular Weight: 178.23
• Product Categories: PIPERIDINE;pharmacetical
• Mol File: 87394-62-5.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 393.998°C at 760 mmHg
• Flash Point: 192.083°C
• Appearance: /
• Density: 1.163g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.596
• PKA: 9.35±0.29(Predicted)
• CAS DataBase Reference: 3-Pyridinamine,2-(1-piperazinyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinamine,2-(1-piperazinyl)-(9CI)(87394-62-5)
• EPA Substance Registry System: 3-Pyridinamine,2-(1-piperazinyl)-(9CI)(87394-62-5)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 87394-62-5(Hazardous Substances Data)

Usage

Chemical Properties

Orange solid

InChI:InChI=1/C9H14N4/c10-8-2-1-3-12-9(8)13-6-4-11-5-7-13/h1-3,11H,4-7,10H2

Upstream product

• 5470-18-8 2-Chloro-3-nitropyridine 
• 87394-48-7 1-(3-nitro-2-pyridinyl)piperazine 

Downstream Products

• 111669-26-2 4-(3-ethylaminopyridin-2-yl)piperazine-1-carboxylic acid tert-butyl ester 
• 111669-24-0 4-[3-(Ethylamino)-2-pyridinyl]-piperazine 
• 111669-25-1 1-[1,1-dimethylethoxycarbonyl]-4-[3-amino-2-pyridinyl]piperazine 

Relevant articles and documents

PYRIMIDO[5,4-d]PYRIMIDINE DERIVATIVES AS ENT INHIBITORS FOR THE TREATMENT OF CANCERS, AND COMBINATION THEREOF WITH ADENOSINE RECEPTOR ANTAGONISTS

The present invention relates to pyrimido[5,4-d]pyrimidine derivatives of formula (I), including pharmaceutically acceptable salts and solvates thereof. Compounds of the invention are inhibitors of ENT family transporter, especially of ENT1, and are useful as therapeutic compounds for the treatment of cancers. The invention also relates to the combined use of the pyrimido[5,4-d]pyrimidine derivatives with an adenosine receptor antagonist, for the treatment of cancers.

Aryl group- or aromatic heterocyclic group-substituted aminoquinolone derivatives and anti-HIV agent

Disclosed are an aryl group- or heterocyclic group-substituted aminoquinolone compound represented by the formula (Ia), (Ib) or (Ic): STR1 wherein each of the substitutents are defined in the specification, or a salt of the compound, and an AIDS curing agent containing the same as an effective ingredient.

Amines useful in producing pharmaceutically active CNS compounds

Disclosed are Δ9(11) -steroids (VI) and amino substituted steroids (XI) which contain an amino group attached to the terminal carbon atom of the C17 -side chain, more particularly amino steroids (Ia and Ib), aromatic steroids (II), Δ16 -steroids (IIIa and IIIb), reduced A-ring steroids (IV), Δ17(20) -steroids (Va and Vb) and Δ9(11) -steroids (VI) which are useful as pharmaceutical agents for treating a number of conditions.