111870-27-0

Basic information

• Product Name: 5-chloro-3-formyl-2-hydroxybenzoic acid
• CAS NO: 111870-27-0
• Molecular Formula: C₈H₅ClO₄
• Molecular Weight: 200.5759
• Mol File: 111870-27-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 328.2°C at 760 mmHg
• Flash Point: 152.3°C
• Density: 1.617g/cm³
• Vapor Pressure: 7.75E-05mmHg at 25°C
• Refractive Index: 1.677
• CAS DataBase Reference: 5-chloro-3-formyl-2-hydroxybenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-3-formyl-2-hydroxybenzoic acid(111870-27-0)
• EPA Substance Registry System: 5-chloro-3-formyl-2-hydroxybenzoic acid(111870-27-0)

Safety Data

• Hazardous Substances Data: 111870-27-0(Hazardous Substances Data)

Upstream product

• 610-04-8 3-formylsalicylic acid 
• 50-00-0 formaldehyd 
• 106-48-9 4-chloro-phenol 
• 111171-18-7 5-chloro-2-hydroxy-3-(hydroxymethyl)benzaldehyde 
• 175136-61-5 6-chloro-8-chloromethyl-4H-benzo[1,3]dioxin 
• 64-19-7 acetic acid 
• 100-97-0 hexamethylenetetramine 
• 321-14-2 5-chloro-2-hydroxybenzoic acid 
• 17026-49-2 4-chloro-2,6-bis(hydroxymethyl)phenol 
• 67-66-3 chloroform 

Downstream Products

• 87633-23-6 methyl 5-chloro-3-formyl-2-hydroxybenzoate 
• 111870-33-8 5-Chloro-N-(4-chloro-phenyl)-3-{[(Z)-4-fluoro-phenylimino]-methyl}-2-hydroxy-benzamide 
• 111870-34-9 5-Chloro-N-(4-fluoro-phenyl)-3-{[(Z)-4-fluoro-phenylimino]-methyl}-2-hydroxy-benzamide 
• 111870-31-6 5-Chloro-N-(4-chloro-phenyl)-2-hydroxy-3-((Z)-2-nitro-vinyl)-benzamide 
• 111870-32-7 5-Chloro-N-(4-fluoro-phenyl)-2-hydroxy-3-((Z)-2-nitro-vinyl)-benzamide 
• 111870-30-5 5-chloro-3-(2-nitroethenyl)salicylanilide 
• 111870-29-2 5-chloro-3-(2-nitroethenyl)salicyloyl chloride 
• 111870-28-1 5-chloro-3-(2-nitroethenyl)salicylic acid 
• 773869-56-0 2,6-bicarboxy-4-chloro-phenol 

Relevant articles and documents

Synthesis of salicylaldehydes from phenols via copper-mediated duff reaction

A copper-mediated Duff reaction for ortho-selective formylation of phenols has been developed. In the presence of copper species, significant improvements of yield and ortho-selectivity of the Duff formylation were achieved, which provides an easy access to salicylaldehydes from phenols.

Benzo-furan derivative

Novel benzo-furan(or -thiophene) derivative of the formula: STR1 wherein R1 is hydrogen atom, a lower alkyl group, a cycloalkyl group, a phenyl-lower alkyl group or a substituted or unsubstituted phenyl group, R2 is hydrogen atom, a lower alkyl group, an acyl group or phenyl group, R3 is hydrogen atom, a halogen atom, nitro group, a lower alkoxy group, amino group or an acylamino group, R4 is a group of the formula: STR2 A is a lower alkylene group optionally substituted with hydroxy group, B is single bond or a lower alkylene group, one of R5 and R6 is hydrogen atom or a lower alkyl group and the other is a lower alkyl group or a phenyl-lower alkyl group, or R5 and R6 combine together with adjacent nitrogen atom to form a heteromonocyclic group, R7 is a lower alkyl group, X is oxygen atom or sulfur atom, Y is oxygen atom, imino group, a lower alkylimino group or a phenyl-lower alkylimino group and a salt thereof are disclosed. Said compound (I) and a salt thereof have a potent inhibitory activity against reflective contraction of urinary bladder.

5-Chloro-3-(2-nitroethenyl)salicylic Acid Anilides and Related Substances, New Polyactive Biocides.

5-Chloro-3-formylsalicylic acid (1) is readily obtained by reaction of 5-chlorosalicylic acid with chloroform in alkali. 1 condenses with nitromethane to give 5-chloro-3-(2-nitroethenyl)salicylic acid (2) which condenses with anilines through its chloride