112129-04-1Relevant academic research and scientific papers
A practical oxidative conversion of aldehydes into N-chloroaldimines
Jin, Can,Wang, Feng,Sun, Bin,Zhuang, Xiaohui
, p. 547 - 551 (2018/11/27)
A novel method for the preparation of N-chloroaldimines from commonly available aromatic aldehydes has been developed. The reaction proceeded effectively by two steps: aldehydes were initially transformed into imines and then chloro-substitution with NaClO2 gave the N-chloroaldimines. This simple protocol allows for the preparation of a variety of aromatic N-chloroaldimines in moderate to excellent yields without the isolation of the imine intermediate. We also found that 3-nitrobenzaldehyde and 4-cyanobenzaldehyde were converted into the related benzonitrile directly under the standard conditions.
Poly(N,N′-dichloro-N-ethylbenzene-1,3-disulfonamide) and N,N,N′,N′-tetrachlorobenzene-1,3-disulfonamide as novel reagents for the synthesis of N-chloroamines, nitriles and aldehydes
Ghorbani-Vaghei, Ramin,Veisi, Hojat
experimental part, p. 945 - 950 (2009/12/01)
The applications of poly(N,N′-dichloro-N-ethylbenzene-1,3- disulfonamide) (PCBS) and N,N,N′,N′-tetrachlorobenzene-1,3- disulfonamide (TCBDA) as novel reagents for the preparation of N,N-dichloroamines, nitriles, and aldehydes from primary amines under various conditions are described. Also, a simple and effective procedure for the direct oxidative conversion of primary alcohols into nitriles was successfully carried out with TCBDA and PCBS in aqueous ammonia. Georg Thieme Verlag Stuttgart.
