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4,6-dichloro-m-cresol, also known as Canertinib, is a chemical compound with the molecular formula C7H6Cl2O. It is an organic compound belonging to the family of phenols, specifically the class of dichlorophenols. Characterized by its faint aromatic smell and white crystalline appearance, 4,6-dichloro-m-cresol is known for its distinctive properties.

1124-07-8

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1124-07-8 Usage

Uses

Used in Agricultural Applications:
4,6-dichloro-m-cresol is used as a fungicide for [application reason] its ability to eliminate fungi and mould which can heavily contaminate crops and slow or halt their growth.
Used in Healthcare Products:
4,6-dichloro-m-cresol is used as an active ingredient in certain healthcare products for [application reason] its antimicrobial properties.
However, due to its toxic nature, 4,6-dichloro-m-cresol may lead to health problems if inhaled, consumed, or comes into contact with skin, and it's also harmful to the environment. It is listed as a hazardous substance under multiple regulations worldwide, hence requiring careful handling and disposal.

Check Digit Verification of cas no

The CAS Registry Mumber 1124-07-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,2 and 4 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1124-07:
(6*1)+(5*1)+(4*2)+(3*4)+(2*0)+(1*7)=38
38 % 10 = 8
So 1124-07-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H6Cl2O/c1-4-2-7(10)6(9)3-5(4)8/h2-3,10H,1H3

1124-07-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,4-Dichloro-5-methylphenol

1.2 Other means of identification

Product number -
Other names 2,4-dichloro-5-methyl-phenol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1124-07-8 SDS

1124-07-8Relevant academic research and scientific papers

Investigations of the reactions of monochloramine and dichloramine with selected phenols: Examination of humic acid models and water contaminants

Heasley, Victor L.,Fisher, Audra M.,Herman, Erica E.,Jacobsen, Faith E.,Miller, Evan W.,Ramirez, Ashley M.,Royer, Nicole R.,Whisenand, Josh M.,Zoetewey, David L.,Shellhamer, Dale F.

, p. 5022 - 5029 (2008/04/18)

The phenols are an important area of investigation because they are substituents in the humic acids and are common contaminants in water. The reactivities and orientations of two common phenols (phenol and m-cresol), and some of their chlorinated intermediates with aqueous monochloroamine and dichloroamine were presented. m-Cresol was more reactive than phenol with both chlorinating agents. NH2Cl and NHCl2 showed extensive reactivity toward the phenols, even the partially chlorinated less reactive intermediates would be expected to fully chlorinate the activated positions in phenolic substituents in the humic acids.

Highly Selective Aromatic Chlorinations. Part 2. The Chlorination of Substituted Phenols, Anisoles, Anilines, and Related Compounds with N-Chloroamines in Acidic Solution

Smith, John R. Lindsay,McKeer, Linda C.,Taylor, Jonathan M.

, p. 385 - 392 (2007/10/02)

Phenols, anisoles, anilines, and related compounds are chlorinated in trifluoroacetic acid at room temperature by N-chlorodialkylamines and N-chlorotrialkylammonium salts.With monsubstituted compounds and their 2- and 3-substituted derivatives the reaction occurs efficiently and selectively at the 4-position.The reactivity of these substrates and the selectivity of their chlorinations are determined by electronic rather than steric effects of the substituent.Blocking the reaction with a substituent at the 4-position generally leads to only poor or moderate yields of the 2-chlorinated product.Evidence for radical and cation radical intermediates has been obtained in the reactions of some of the 4-substituted reactants and the mechanism of chlorination is discussed in the light of these findings.The reactions of selected substrates have been scaled up to give laboratory syntheses.

HIGH SITE-SELECTIVITY IN THE CHLORINATION OF ELECTRON-RICH AROMATIC COMPOUNDS BY N-CHLORAMMONIUM SALTS.

Smith, John R. Lindsay,McKeer, Linda C.

, p. 3117 - 3120 (2007/10/02)

N-Chlorammonium salts are efficient and very site-selective monochlorinating agents for electron-rich aromatic compounds.

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