24731-36-0Relevant academic research and scientific papers
Trimethylsilyl cyanide addition to carbonyl compounds under neutral condition catalyzed by iodine
Azizi, Najmedin,Saidi, Mohammad R.
, p. 2111 - 2115 (2003)
Reaction of trimethylsilyl cyanide with aliphatic or aromatic aldehydes and ketones in the presence of a catalytic amount of elemental iodine produced the corresponding cyanohydrin trimethylsilyl ethers in very short time and high yields.
Pickering emulsion droplets hosting ionic liquid catalysts for continuous-flow cyanosilylation reaction
Meng, Zhixin,Zhang, Ming,Yang, Hengquan
, p. 627 - 633 (2019)
An IL-catalyzed cyanosilylation reaction is an important route for synthesis of many fine chemicals, but it is currently conducted in a batch manner. Herein, we have developed a novel method to "immobilize" IL catalysts for continuous-flow reaction based
Solvent-free heterogeneous catalysis for cyanosilylation in a modified sodalite-type Cu(II)-MOF
Zhang, Ling-Juan,Han, Cai-Yun,Dang, Qin-Qin,Wang, Yan-Hong,Zhang, Xian-Ming
, p. 24293 - 24298 (2015)
Solvothermal reaction of Cu(OAc)2 and H3BTT·2HCl generated a sodalite-type metal-organic framework [(Cu4O0.27Cl0.73)3(H0.5BTT)8(H2O)12]·3MeOH·9DM
Controllable Synthesis and Catalytic Performance of Nanocrystals of Rare-Earth-Polyoxometalates
Li, Shujun,Zhou, Yanfang,Peng, Qingpo,Wang, Ruoya,Feng, Xiaoge,Liu, Shuxia,Ma, Xiaoming,Ma, Nana,Zhang, Jie,Chang, Yi,Zheng, Zhiping,Chen, Xuenian
, p. 6624 - 6631 (2018)
Large-scale isolation of nanocrystals of rare-earth-polyoxometalates (RE-POMs) catalysts is important in fundamental research and applications. Here, we synthesized a family of monomeric RE-POMs by the self-assembly of Ta/W mixed-addendum POM {P2/su
Determination, par spectrometries infrarouge et Raman, de la stereochimie de cyclohexylcyanhydrines O-trimethylsilylees
Marchand, Annette,Gerval, Pierre,Picard, Jean-Paul
, p. 1735 - 1744 (1991)
A homogeneous series of α-trimethylsiloxynitriles 1-8, obtained by cyanosilylation of cyclohexanones, was investigated by Raman and IR spectroscopies.This study yielded information that complements previous fragmentary NMR results.It was shown that both p
Niobium phytate prepared from phytic acid and NbCl5: A highly efficient and heterogeneous acid catalyst
Xue, Zhimin,Zhang, Yuwei,Li, Guofeng,Wang, Jinfang,Zhao, Wancheng,Mu, Tiancheng
, p. 1070 - 1076 (2016)
The preparation of functional catalysts using naturally-occurring building blocks is of great importance. In this work, we designed a functional heterogeneous acid catalyst, niobium phytate, using phytic acid, which could be obtained from the seeds and grains of plants, as the building block to react with NbCl5. The prepared niobium phytate was characterized by XRD, FT-IR, XPS, SEM, TEM, NH3-TPD and N2 adsorption-desorption examinations. Niobium phytate showed very high activity for both cyanosilylation of carbonyl compounds and dehydration of carbohydrates. It was also found that niobium phytate had higher activity than commercial Nb2O5. In addition, niobium phytate could be easily recovered and reused without reducing the reaction activity considerably. Further study indicated that both higher acidity and lower crystallinity contributed significantly to the excellent catalytic performance of niobium phytate. The findings in this work provide insights into the design of new functional catalysts using naturally-occurring building blocks for various organic reactions.
A micro-environment tuning approach for enhancing the catalytic capabilities of lanthanide containing polyoxometalate in the cyanosilylation of ketones
Li, Sang-Hao,Lin, Ming-Yuan,Nie, Yan-Mei,Yan, Jun
, p. 3809 - 3812 (2020)
The as-synthesized (TBA)8H5[Nd(SiW11O39)2] manifested high catalytic activity for cyanosilylation of ketones, and its catalytic activity could be improved further through rational design of the reacti
Supported ionic liquid-like phases as organocatalysts for the solvent-free cyanosilylation of carbonyl compounds: From batch to continuous flow process
Martin, Sergio,Porcar, Raul,Peris, Edgar,Burguete, Maria Isabel,Garcia-Verdugo, Eduardo,Luis, Santiago V.
, p. 1639 - 1647 (2014)
Supported ionic liquid-like phases (SILLPs) are able to efficiently catalyse the cyanosilylation of carbonyl compounds using trimethylsilyl cyanide under solvent-free conditions. These organic catalysts were efficient for various carbonyl compounds includ
Synthesis, characterization, crystal structure of magnesium compound based 3, 3′, 5, 5′-azobenzentetracarboxylic acid and application as high-performance heterogeneous catalyst for cyanosilylation
Li, Yong-Peng,Zhang, Ling-Juan,Ji, Wen-Juan
, p. 607 - 614 (2017)
A novel coordination compound with the formula {[H3O]2[Mg(ABTC)(DMI)2]}n (1) (H4ABTC?=?3,3′,5,5′-azobenzene-tetracarboxylic acid, DMI?=?1,3-dimethy-2-imidazolidinone) as synthesized under solvothermal
Application of an Electrochemical Microflow Reactor for Cyanosilylation: Machine Learning-Assisted Exploration of Suitable Reaction Conditions for Semi-Large-Scale Synthesis
Sato, Eisuke,Fujii, Mayu,Tanaka, Hiroki,Mitsudo, Koichi,Kondo, Masaru,Takizawa, Shinobu,Sasai, Hiroaki,Washio, Takeshi,Ishikawa, Kazunori,Suga, Seiji
supporting information, p. 16035 - 16044 (2021/09/02)
Cyanosilylation of carbonyl compounds provides protected cyanohydrins, which can be converted into many kinds of compounds such as amino alcohols, amides, esters, and carboxylic acids. In particular, the use of trimethylsilyl cyanide as the sole carbon source can avoid the need for more toxic inorganic cyanides. In this paper, we describe an electrochemically initiated cyanosilylation of carbonyl compounds and its application to a microflow reactor. Furthermore, to identify suitable reaction conditions, which reflect considerations beyond simply a high yield, we demonstrate machine learning-assisted optimization. Machine learning can be used to adjust the current and flow rate at the same time and identify the conditions needed to achieve the best productivity.
