112585-34-9

Basic information

• Product Name: 2H-Pyran-2,3(4H)-dione, dihydro-, 3-(phenylhydrazone), (Z)-
• CAS NO: 112585-34-9
• Molecular Formula: C11H12N2O2
• Molecular Weight: 204.228
• Mol File: 112585-34-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2H-Pyran-2,3(4H)-dione, dihydro-, 3-(phenylhydrazone), (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyran-2,3(4H)-dione, dihydro-, 3-(phenylhydrazone), (Z)-(112585-34-9)
• EPA Substance Registry System: 2H-Pyran-2,3(4H)-dione, dihydro-, 3-(phenylhydrazone), (Z)-(112585-34-9)

Safety Data

• Hazardous Substances Data: 112585-34-9(Hazardous Substances Data)

Upstream product

• 42564-36-3 oxo-(2-oxotetrahydrofuran-3-yl)acetic acid ethyl ester 
• 100-63-0 phenylhydrazine 
• 62-53-3 aniline 
• 110977-73-6 α-Ethoxalyl-γ-butyrolacton 
• 7664-93-9 sulfuric acid 
• 127-09-3 sodium acetate 
• 64-19-7 acetic acid 

Downstream Products

• 6250-88-0 4,9-Dihydropyrano<3,4-b>indol-1(3H)-on 
• 13100-00-0 1,2,3,4-tetrahydro-2-methyl-9H-pyrido[3,4-b]indole 

Relevant articles and documents

Indoles, VI: Lactamisation of 4,9-Dihydropyranoindol-1(3H)-ones with Methylamine.- A New Synthetic Route to Strychnocarpine and its Derivatives

The lactamisation of the pyranoindolones 3a-g - available from 1 or 2 -represents a simple synthesis of strychnocarpine (4a) and its substituted derivatives 4b-g, 5b,c.Reduction gives the tetrahydro-β-carbolines 6a-d,f,h.

Lactones, XVI: Synthesis of 4,9-Dihydropyranoindol-1(3H)-ones from α-Ethoxalyl-δ-valerolactone

Treatment of α-ethoxalyl-δ-valerolactone (1) with diazotized anilines and indolization of the intermediate hydrazones 4 leads to the pyranoindolones 5.Compared to the recently reported reaction of α-ethoxalyl-γ-butyrolactone with arylhydrazines2), this synthesis is more versatile with regard to variation of substituents at the aromatic ring.Stereochemistry and reactivity of the α-arylhydrazonolactones are discussed.