112635-77-5Relevant academic research and scientific papers
A flexible enantioselective synthesis of (+)-centrolobine and 5-epi-diospongin-A using asymmetric transfer hydrogenation/tandem Grubbs cross-metathesis/oxy-Michael reaction as key steps
Kumaraswamy, Gullapalli,Rambabu, Dasa
, p. 196 - 201 (2013/04/10)
An efficient enantioselective synthesis of (+)-centrolobine and 5-epi-diospongin-A was achieved by the use of asymmetric transfer hydrogenation (ATH)/tandem Grubbs cross-metathesis/oxy-Michael reaction. Furthermore, this strategy allows for diastereodiver
Chemoenzymatic synthesis of α-Hydroxy-β-methyl-γ-hydroxy esters: Role of the keto-enol equilibrium to control the stereoselective hydrogenation in a key step
Milagre, Cintia D. F.,Milagre, Humberto M. S.,Moran, Paula J. S.,Rodrigues, J. Augusto R.
experimental part, p. 1410 - 1418 (2010/05/19)
"Chemical Equation Presented" α-Hydroxy-β-methyl- γ-hydroxy esters not only are found in many natural products and potent drugs but also are useful intermediates in organic synthesis due to their highly functionalized skeleton that can be further manipula
Studies on the Stereochemical Control of Fermenting Baker's Yeast Mediated Reductions: Some 3- and 4-Oxo Esters
Manzocchi, Ada,Casati, Rosangela,Fiecchi, Alberto,Santaniello, Enzo
, p. 2753 - 2758 (2007/10/02)
Ethyl 4-benzyloxy-3-oxobutanoate (1c) is reduced by fermenting baker's yeast with stereochemical control which is dependent on the yeast: substrate ratio and the presence or absence of ethanol.Contrary to earlier reports, ethyl levulinate (3a) can be ster
