133271-05-3Relevant articles and documents
A flexible enantioselective synthesis of (+)-centrolobine and 5-epi-diospongin-A using asymmetric transfer hydrogenation/tandem Grubbs cross-metathesis/oxy-Michael reaction as key steps
Kumaraswamy, Gullapalli,Rambabu, Dasa
, p. 196 - 201 (2013/04/10)
An efficient enantioselective synthesis of (+)-centrolobine and 5-epi-diospongin-A was achieved by the use of asymmetric transfer hydrogenation (ATH)/tandem Grubbs cross-metathesis/oxy-Michael reaction. Furthermore, this strategy allows for diastereodiver
A concise total synthesis of diospongins A and B
Sabitha, Gowravaram,Padmaja, Pannala,Yadav, Jhillu S.
scheme or table, p. 2235 - 2239 (2009/03/12)
The total synthesis of the diarylheptanoids (-)-diospongin A (1) and B (2) was achieved stereoselectively via the δ-lactone intermediate 6. The key reactions involved are a stereoselective reduction of β-keto ester and the Horner-Wadsworth-Emmons and intramolecular oxy-Michael reactions.
Remote asymmetric induction with vinylketene silyl N,O-acetal
Shirokawa, Shin-Ichi,Kamiyama, Masato,Nakamura, Tomoaki,Okada, Masakazu,Nakazaki, Atsuo,Hosokawa, Seijiro,Kobayashi, Susumu
, p. 13604 - 13605 (2007/10/03)
A highly regio- and diastereoselective TiCl4-mediated vinylogous Mukaiyama aldol reaction using the chiral vinylketene silyl N,O-acetal has been developed. The present vinylogous Mukaiyama aldol reaction provides a unique and effective means of
