113133-46-3Relevant academic research and scientific papers
Acid-catalyzed reaction of 2-hydroxycyclobutanone with benzylic alcohols
Martis, Alberto,Luridiana, Alberto,Frongia, Angelo,Arca, Massimiliano,Sarais, Giorgia,Aitken, David J.,Guillot, Regis,Secci, Francesco
, p. 10053 - 10063 (2017/12/26)
The acid-promoted syntheses of 2-(benzyloxy)cyclobutanones and bis(benzyloxy)dioxatricyclo decanes were achieved starting from 2-hydroxycyclobutanone and variously functionalized benzyl alcohols. The reaction sequences afforded the desired products in good to high yields and in a solvent-dependent chemoselective fashion.
Palladium-catalyzed selective anti-markovnikov oxidation of allylic esters
Dong, Jia Jia,Fananas-Mastral, Martin,Alsters, Paul L.,Browne, Wesley R.,Feringa, Ben L.
, p. 5561 - 5565 (2013/06/27)
An aldol alternative: The palladium(II)-catalyzed anti-Markovnikov oxidation of allylic esters to aldehydes at room temperature provides a viable alternative to valuable cross aldol products. High regioselectivity towards the aldehyde product was achieved using the ester protecting group for the allylic alcohol. Rapid isomerization and the much higher rate of oxidation of the branched isomer result in the same product forming from both linear and branched allylic esters. Copyright
Optical resolution of acyclic α-hydroxy ketone derivatives by inclusion complexation
Matsumoto, Kazutsugu,Okamoto, Tomomi,Otsuka, Keiko
, p. 2051 - 2056 (2007/10/03)
A new method for the preparation of optically active acyclic α-hydroxy ketone derivatives by thermodynamic resolution using a chiral host compound is described. We examined the resolution of racemic 2-benzyloxy-3-pentanone with chiral host compounds in va
New synthetic route to C2-symmetric 2,2′-bipyridines: Synthesis of (6R,6′R,8R,8′R)-6,8,6′, 8′-bismethano-7,7,7′,7′-tetramethyl- 5,5′,6,6′,7,7′,8,8′-octahydro-2,2′-biquinoline
Chelucci,Saba
, p. 3161 - 3166 (2007/10/03)
A generalizable procedure to C2-symmetric 2,2′-bipyridines based on two consecutive constructions of the pyridine rings is reported. As an example of this strategy the title bipyridine has been prepared in four steps from 3-benzyloxy-2-butanone
Enethiolizable thioacylsilanes as intermediates for the synthesis of thietanols, thiolanols, and thianols
Bonini, Bianca F.,Franchini, Mauro Comes,Fochi, Mariafrancesca,Mangini, Simone,Mazzanti, Germana,Ricci, Alfredo
, p. 2391 - 2399 (2007/10/03)
Thietanols, thiolanols, and thianols (tetrahydro-2H-thiopyran-3-ols) can be obtained by a fluoride-mediated cyclization of (Z)-α-silyl vinyl sulfides containing an ω-carbonyl function in the chain bonded to the sulfur.
THE NEF REACTION ON TRIALKYLSILYL NITRONATES PROMOTED BY m-CHLOROPERBENZOIC ACID, AN EFFICIENT ROUTE TO α-ALKOXYKETONES FROM NITROALKANES
Aizpurus, J. M.,Oiarbide, M.,Palomo, C.
, p. 5361 - 5364 (2007/10/02)
Treatment of a nitroalkene with nucleophiles, followed by silylation of the resulting nitroalkane and subsequent treatment with m-chloroperbenzoic acid provides α-functionalized carbonyl compounds in good yields.
THE REACTION OF α-STANNYLMETHYLLITHIUM WITH ESTERS
Sato, Tadashi,Matsuoka, Hiroharu,Igarashi, Tsutomu,Murayama, Eigoro
, p. 4339 - 4342 (2007/10/02)
Ketonic compounds were prepared from esters using α-stannylmethyllithium as the reagent.
