113137-82-9Relevant academic research and scientific papers
AMINOMETHYLATION OF 5-SUBSTITUTED TETRAZOLES
Binda, M.,Dziklinska, A.,Hachiam, A.F.H.,Plenkiewicz, J.
, p. 1257 - 1261 (2007/10/02)
The Mannich reaction of 5-substituted tetrazoles with formaldehyde and secondary amines was described.Some of the synthesized 2-(N,N-dialkyl-aminomethyl)-5-substituted tetrazoles on treatment with aliphatic ketones gave the corresponding 3-(5-substituted tetrazolyl-2)-1 ones in moderate yields.
THE MICHAEL TYPE ADDITIONS OF TETRAZOLE DERIVATIVES TO DOUBLE AND TRIPLE CARBON-CARBON BONDS
Dziklinska, H.,Dzierzgowski, S.,Jezewski, A.,Plenkiewicz, J.
, p. 277 - 284 (2007/10/02)
The reactions of 5-substituted tetrazoles, 1-substituted tetrazolin-5-ones and 5-substituted 1-hydroxytetrazoles with ethylene derivatives possessing electron withdrawing substituents were found to be of practical value in preparing variously substituted
TETRAZOLES. XXVII. KINETICS OF THE REACTION TRIETHYLAMMONIUM SALTS OF 5-ARYL-TETRAZOLES WITH METHYL VINYL KETONE
Poplavskii, V. S.,Titova, I. E.,Ostrovskii, V. A.,Koldobskii, G. I.
, p. 1971 - 1974 (2007/10/02)
The alkylation of the triethylammonium salts of 5-aryltetrazoles by methyl vinyl ketone in DMFA takes place irreversibly and leads to the formation of 4-(aryltetrazole-2-yl)-2-butanones.The rate-determining stage is the addition of the 5- aryltetrazole salt to the polarized double bond of the methyl vinyl ketone.The reaction rate constants correlate with the electronic ? constans of the substituents in the benzene ring.The high selectivity of alkylation is determined by the rigorous steric demands to the structural features of the reagents.
TETRAZOLES. XXII. KINETICS OF THE REACTION OF THE TRIETHYLAMMONIUM SALT OF 5-PHENYLTETRAZOLE WITH METHYL VINYL KETONE
Titova, I. E.,Poplavskii, V. S.,Ostrovskii, V. A.,Erusalimskii, G. B.,Tereshchenko, G. F.,Koldobskii, G. I.
, p. 977 - 981 (2007/10/02)
The kinetics of the reaction of 5-phenyltetrazole triethylammonium salt with methyl vinyl ketone in acetonitrile and DMFA were studied.At a concentration of cca. 2.5E-01 M the 5-phenyltetrazole triethylammonium salt is associated, and an intimate ion pair, formed with participation of a hydrogen bond, enters into reaction with the methyl vinyl ketone.The controlling stage is the formation of the anionic intermediate, the subsequent protonation of which leads to the final reaction products.
