113278-68-5

Basic information

• Product Name: (R)-(-)-2,2-DIMETHYL-5-OXO-1,3-DIOXOLANE-4-ACETIC ACID
• Synonyms: (R)-(-)-2,2-Dimethyl-5-oxo-1,3-dioxolane-4-acetic acid 95%;[(4R)-2,2-DIMETHYL-5-OXO-1,3-DIOXOLAN-4-YL]ACETIC ACID;(R)-(-)-2,2-DIMETHYL-5-OXO-1,3-DIOXOLANE-4-ACETIC ACID;(R)-(-)-2,2-dimethyl-5-oxo-1,3-dioxolane-4-acetic;[(R)-2,2-Dimethyl-5-oxo-1,3-dioxolan-4-yl]acetic Acid;2-((R)-2,2-Dimethyl-5-oxo-1,3-dioxolan-4-yl)acetic Acid;(R)-2,2-DiMethyl-5-oxo-;(R)-(-)-2,2-DiMethyl-5-oxo-1,3-dioxolane-4-acetic acid,95%
• CAS NO: 113278-68-5
• Molecular Formula: C₇H₁₀O₅
• Molecular Weight: 174.15
• Product Categories: Chiral Reagents;Heterocycles;Carboxylic Acids;Chiral Building Blocks;Organic Building Blocks
• Mol File: 113278-68-5.mol
• Article Data: 43

Chemical Properties

• Melting Point: 95-98°C
• Boiling Point: 341.4°Cat760mmHg
• Flash Point: 143.7°C
• Appearance: /
• Density: 1.262g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.455
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Dichloromethane, Ethyl Acetate, Methanol
• PKA: 3.96±0.10(Predicted)
• CAS DataBase Reference: (R)-(-)-2,2-DIMETHYL-5-OXO-1,3-DIOXOLANE-4-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(-)-2,2-DIMETHYL-5-OXO-1,3-DIOXOLANE-4-ACETIC ACID(113278-68-5)
• EPA Substance Registry System: (R)-(-)-2,2-DIMETHYL-5-OXO-1,3-DIOXOLANE-4-ACETIC ACID(113278-68-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 113278-68-5(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

Uses

Different sources of media describe the Uses of 113278-68-5 differently. You can refer to the following data:
1. An optically active inhibitor
2. An optically active inhibitor.

General Description

(R)-(?)-2,2-Dimethyl-5-oxo-1,3-dioxolane-4-acetic acid can be used as an intermediate/starting material in the synthesis of (R)-isoserine, a glucagon receptor antagonist, blepharismone, and pheromone of Blepharisma japonicum.

InChI:InChI=1/C7H10O5/c1-7(2)11-4(3-5(8)9)6(10)12-7/h4H,3H2,1-2H3,(H,8,9)/t4-/m1/s1

Upstream product

• 97-67-6 (S)-Malic acid 
• 116-11-0 2-Methoxypropene 
• 636-61-3 D-Malic acid 
• 617-48-1 malic acid 
• 77-76-9 2,2-dimethoxy-propane 
• 174563-88-3 (5R)-5-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolan-4-one 
• 1738-69-8 L-Leucine benzyl ester 
• 67-64-1 acetone 

Downstream Products

• 52079-23-9 (3S)-3-hydroxydihydrofuran-2(3H)-one 
• 124724-88-5 (5S)-5-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolan-4-one 
• 161125-36-6 Fmoc-(R)-iSer-OH 
• 19444-84-9 3-deoxy-L-glycero-tetronolactone 
• 242810-01-1 2-[2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]acetic acid benzyl ester 
• 265659-42-5 7-(1,2-O-isopropylidene-malyl) baccatin III 
• 870460-32-5 2,6-di-tert-butyl-4-(1-{3,5-di-tert-butyl-4-[2-(2,2-dimethyl-[1,3]dioxolan-4(S)-yl)-ethoxy]-phenylsulfanyl}-1-methyl-ethylsulfanyl)-phenol 
• 164264-14-6 (3S)-3-[(1,1-Dimethylethyl)dimethylsilyloxy]-oxolan-2-one 
• 1439400-05-1 C₂₃H₂₅FN₆O₅S₂ 
• 1428655-46-2 benzyl 3β-[(S)-2-(2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl)acetyloxy]olean-12-en-28-oate 
• 1428655-48-4 benzyloxycarbonylmethyl 3β-[(S)-2-(2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl)acetyloxy]olean-12-en-28-oate 

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