1135-56-4Relevant academic research and scientific papers
Fluorescence sensing due to allosteric switching of pyrene functionalized cis-cyclohexane-1,3-dicarboxylate
Monahan, Carol,Bien, Jeffrey T.,Smith, Bradley D.
, p. 431 - 432 (1998)
The excimer/monomer fluorescence ratio for a pyrene functionalized cis-cyclohexane-1,3-dicarboxylate decreases upon titration with divalent and monovalent metal cations, as well as strong and weak acids.
Remote Enzyme-Coupled Amine Release
Menger, F. M.,Ladika, M.
, p. 3006 - 3007 (2007/10/02)
A remote enzyme-coupled amine release system has been developed in which biochemical and chemical "demasking" processes are sequentially linked via an enforced 1,3-diaxial disposition.Thus, pig liver esterase hydrolyzes an ester to an acid, and the acid promotes a fast intramolecular cleavage of an amide to an amine.The sequence has potential pharmacokinetic relevance because it allows enzyme-specific discharge of amine-based drugs following their trans-membrane journey as uncharged amides.
