1137-69-5 Usage
General Description
2-Chlorophenazine is a chemical compound with the molecular formula C12H7ClN2. It is a pale yellow crystalline solid that is insoluble in water but soluble in organic solvents. 2-Chlorophenazine is a chlorinated derivative of phenazine and is commonly used as an intermediate in the synthesis of pharmaceuticals, dyes, and other organic compounds. It has antibacterial and antifungal properties and can be used as an active ingredient in some disinfectants and antiseptics. Additionally, 2-Chlorophenazine has been studied for its potential use in cancer treatment due to its ability to induce apoptosis in cancer cells. However, it is important to handle this compound with care as it can be hazardous if ingested, inhaled, or absorbed through the skin.
Check Digit Verification of cas no
The CAS Registry Mumber 1137-69-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,3 and 7 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1137-69:
(6*1)+(5*1)+(4*3)+(3*7)+(2*6)+(1*9)=65
65 % 10 = 5
So 1137-69-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H7ClN2/c13-8-5-6-11-12(7-8)15-10-4-2-1-3-9(10)14-11/h1-7H
1137-69-5Relevant articles and documents
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Vivian,Hartwell
, p. 1065,1068 (1953)
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Preparation method of phenazine compound
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Paragraph 0021-0032; 0035; 0039, (2021/09/26)
To the method, a phenazine compound is prepared through continuous ortho C-H functionalization, nitroso insertion and decarboxylation processes of aryl carbamic acid, wherein a carboxyl amino group serves as a trace-free positioning group.
Reactivity and substituent effects in the cyclization of N-aryl-2-nitrosoanilines to phenazines
Wróbel, Zbigniew,Plichta, Karolina,Kwast, Andrzej
, p. 3147 - 3152 (2017/05/08)
Reactivity of variously substituted N-aryl-2-nitrosoanilines in the reaction of cyclization leading to phenazine derivatives, carried out in the presence of N,O-bis(trimethylsilyl)acetamide (BSA), was estimated on the base of the observed reaction times. A strong opposite effect of substituents located at position para to the nitroso group and those located para to the amino group in the side ring was observed. Mechanistic explanation, based on the electronic properties of the substituents and their mesomeric effects, was presented. The usefulness of the obtained data for the designed syntheses of phenazines was exposed.
