113964-72-0

Basic information

• Product Name: triphenyl(pyridin-4-yl)phosphonium trifluoromethanesulfonate
• Synonyms: triphenyl(pyridin-4-yl)phosphonium trifluoromethanesulfonate
• CAS NO: 113964-72-0
• Molecular Weight: 489.455
• Mol File: 113964-72-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: triphenyl(pyridin-4-yl)phosphonium trifluoromethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: triphenyl(pyridin-4-yl)phosphonium trifluoromethanesulfonate(113964-72-0)
• EPA Substance Registry System: triphenyl(pyridin-4-yl)phosphonium trifluoromethanesulfonate(113964-72-0)

Safety Data

• Hazardous Substances Data: 113964-72-0(Hazardous Substances Data)

Upstream product

• 110-86-1 pyridine 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 603-35-0 triphenylphosphine 

Downstream Products

• 553-26-4 4,4'-bipyridine 
• 33974-28-6 α-(4-methylphenyl)-4-pyridinemethanol 
• 116928-29-1 <2-(4-Methylbenzoyl)-4-pyridyl>triphenylphosphonium-trifluormethansulfonat 
• 939-23-1 p-phenylpyridine 
• 21308-82-7 4-(thiophen-3-yl)-pyridine 
• 870863-00-6 4-(1-methyl-1H-pyrazol-4-yl)pyridine 
• 70581-00-9 1-(4-(pyridin-4-yl)phenyl)ethan-1-one 
• 144397-70-6 4-(pyridin-4-yl)benzonitrile 
• 4282-45-5 4-(4-nitrophenyl)pyridine 
• 106047-17-0 4-Pyridin-4-yl-benzoic acid methyl ester 
• 4467-15-6 4-(2-chlorophenyl)pyridine 
• 1166397-62-1 4-(3,5-difluorophenyl)pyridine 
• 59656-60-9 N-(4-(pyridin-4-yl)phenyl)acetamide 
• 1110656-21-7 4-(3-(tert-butyl)phenyl)pyridine 

Relevant articles and documents

Phosphonium Salts as Pseudohalides: Regioselective Nickel-Catalyzed Cross-Coupling of Complex Pyridines and Diazines

Heterobiaryls are important pharmacophores that are challenging to prepare by traditional cross-coupling methods. An alternative approach is presented where pyridines and diazines are converted into heteroaryl phosphonium salts and coupled with aryl boronic acids. Nickel catalysts are unique for selective heteroaryl transfer, and the reaction has a broad substrate scope that includes complex pharmaceuticals. Phosphonium ions also display orthogonal reactivity in cross-couplings compared to halides, enabling chemoselective palladium- and nickel-catalyzed coupling sequences.

NEUE METHODE ZUR REGIOSPEZIFISCHEN SUBSTITUTION EINIGER REAKTIONSTRAEGER N-HETEROAROMATISCHER RINGSYSTEME

N-Trifluoromethanesulfonyl-heteroarylium salts 1 react with phosphanes 2 to give the C4- or C2-substituted products 4 or 5.By means of a similar procedure, bisphosphonium salts 6 and 7 are formed.The reaction of sodium azide (8), and 6 yields the iminophosphorane 10 via the intermediate 9.