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1141-45-3

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1141-45-3 Usage

General Description

3-(2-NAPHTHYLTHIO)PROPIONIC ACID is a chemical compound that belongs to the class of thioether carboxylic acids. It is commonly used as an intermediate in the synthesis of pharmaceuticals and Agrochemicals. It is also known for its ability to inhibit the production of leukotrienes, which are involved in inflammatory and allergic reactions. The compound has been studied for its potential use in the treatment of asthma and inflammation-related conditions. Additionally, it has been investigated for its antioxidant properties and potential use in the food industry as a preservative. Overall, 3-(2-NAPHTHYLTHIO)PROPIONIC ACID has a wide range of potential applications in various fields, making it an important chemical compound in research and industry.

Check Digit Verification of cas no

The CAS Registry Mumber 1141-45-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,4 and 1 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1141-45:
(6*1)+(5*1)+(4*4)+(3*1)+(2*4)+(1*5)=43
43 % 10 = 3
So 1141-45-3 is a valid CAS Registry Number.
InChI:InChI=1/C13H12O2S/c14-13(15)7-8-16-12-6-5-10-3-1-2-4-11(10)9-12/h1-6,9H,7-8H2,(H,14,15)

1141-45-3 Well-known Company Product Price

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  • Alfa Aesar

  • (L06208)  3-(2-Naphthylthio)propionic acid, 97%   

  • 1141-45-3

  • 1g

  • 730.0CNY

  • Detail
  • Alfa Aesar

  • (L06208)  3-(2-Naphthylthio)propionic acid, 97%   

  • 1141-45-3

  • 5g

  • 2547.0CNY

  • Detail

1141-45-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-naphthalen-2-ylsulfanylpropanoic acid

1.2 Other means of identification

Product number -
Other names 3-(2-NAPHTHYLTHIO)PROPIONIC ACID

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1141-45-3 SDS

1141-45-3Relevant articles and documents

Cu(I)-Catalyzed Enantioselective Alkynylation of Thiochromones

Chang, Xiaoyong,Lin, Zhenyang,Meng, Ling,Ngai, Ka Yan,Wang, Jun

supporting information, p. 1155 - 1159 (2020/02/26)

A highly efficient asymmetric synthesis of chiral thiochromanones is developed via Cu(I)/phosphoramidite catalyzed asymmetric alkynylation of thiochromones under mild reaction conditions. The catalyst system is tolerant of various thiochromone precursors and terminal alkynes. The established asymmetric transformation provides different enatiomeric-enriched thiochromanones with more molecular complexity and enables access to chiral thioflavanones, a subgroup of flavonoid by further functionalization.

Cu-Catalyzed Conjugate Addition of Grignard Reagents to Thiochromones: An Enantioselective Pathway for Accessing 2-Alkylthiochromanones

Luo, Shihui,Meng, Ling,Yang, Qingxiong,Wang, Jun

supporting information, p. 2071 - 2075 (2018/09/18)

The enantioselective incorporation of alkyl groups in thiochromones was realized for the first time by a Cu/(R, S)-PPF-P t Bu 2 -catalyzed conjugate addition of Grignard reagents to thiochromones. With this method, a series of 2-methylthiochromanones were obtained in good yields (up to 96% yield) with moderate-to-good ee values (up to 87% ee). The established method expedites the synthesis of a large library of chiral thiochromanones for further synthetic applications and biological studies.

Synthesis and biochemical evaluation of thiochromanone thiosemicarbazone analogues as inhibitors of cathepsin L

Song, Jiangli,Jones, Lindsay M.,Kumar, G. D. Kishore,Conner, Elizabeth S.,Bayeh, Liela,Chavarria, Gustavo E.,Charlton-Sevcik, Amanda K.,Chen, Shen-En,Chaplin, David J.,Trawick, Mary Lynn,Pinney, Kevin G.

experimental part, p. 450 - 453 (2012/09/25)

A series of 36 thiosemicarbazone analogues containing the thiochromanone molecular scaffold functionalized primarily at the C-6 position were prepared by chemical synthesis and evaluated as inhibitors of cathepsins L and B. The most promising inhibitors f

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