1142224-45-0

Basic information

• Product Name: methyl 3-(5,5-dimethylcyclopent-1-enyl)-4-(trifluoromethylsulfonyloxy)benzoate
• Synonyms: methyl 3-(5,5-dimethylcyclopent-1-enyl)-4-(trifluoromethylsulfonyloxy)benzoate
• CAS NO: 1142224-45-0
• Molecular Weight: 378.369
• Mol File: 1142224-45-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 3-(5,5-dimethylcyclopent-1-enyl)-4-(trifluoromethylsulfonyloxy)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(5,5-dimethylcyclopent-1-enyl)-4-(trifluoromethylsulfonyloxy)benzoate(1142224-45-0)
• EPA Substance Registry System: methyl 3-(5,5-dimethylcyclopent-1-enyl)-4-(trifluoromethylsulfonyloxy)benzoate(1142224-45-0)

Safety Data

• Hazardous Substances Data: 1142224-45-0(Hazardous Substances Data)

Upstream product

• 37595-74-7 N,N-phenylbistrifluoromethane-sulfonimide 
• 1142224-43-8 methyl 3-(5,5-dimethylcyclopent-1-enyl)-4-hydroxybenzoate 
• 1142224-42-7 methyl 3-(5,5-dimethylcyclopent-1-enyl)-4-(tetrahydro-2H-pyran-2-yloxy)benzoate 
• 1142224-41-6 methyl 3-bromo-4-(tetrahydro-2H-pyran-2-yloxy)benzoate 
• 1011531-89-7 2-(5,5-dimethylcyclopent-1-en-1-yl)-4,4,5,5-tetramethyl-1 ,3 ,2-dioxaborolane 
• 153580-03-1 5,5-dimethylcyclopent-1-en-1-yl trifluoromethanesulfonate 
• 4541-32-6 2,2-dimethylcyclopentanone 
• 29415-97-2 methyl 3-bromo-4-hydroxybenzoate 
• 14348-41-5 3-bromo-4-hydroxy-benzoic acid 

Downstream Products

• 1142226-22-9 methyl 2-(5,5-dimethyl-1-cyclopenten-1-yl)-5'-(ethyIoxy)-2'-fluoro-1,1'-biphenyl-4-carboxylate 
• 1142225-00-0 methyl 3-(5,5-dimethylcyclopent-1-enyl)-4-(5-fluoro-2-methoxypyridin-4-yl)benzoate 
• 1142223-31-1 (2-(5,5-dimethyl-1-cyclopenten-1-yl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-yl)methanol 
• 1142223-37-7 4-(chloromethyl)-2-(5,5-dimethyl-1-cyclopenten-1-yl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl 
• 1142214-62-7 [3H]-AM 1638 
• 1393841-41-2 C₃₄H₃₇FO₄ 
• 1142225-01-1 (3-(5,5-dimethylcyclopent-1-enyl)-4-(5-fluoro-2-methoxypyridin-4-yl)phenyl)methanol 
• 1142231-87-5 (3-((R)-2,2-dimethylcyclopentyl)-4-(5-fluoro-2-methoxypyridin-4-yl)phenyl)methanol 
• 1142231-86-4 (3-((S)-2,2-dimethylcyclopentyl)-4-(5-fluoro-2-methoxypyridin-4-yl)phenyl)methanol 
• 1187197-76-7 4-(4-(chloromethyl)-2-((R)-2,2-dimethylcyclopentyl)phenyl)-5-fluoro-2-methoxypyridine 
• 1222089-36-2 (1R,2R)-7'-((3-((R)-2,2-dimethylcyclopentyl)-4-(5-fluoro-2-methoxypyridin-4-yl)benzyl)oxy)-8'-fluoro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalene]-2-carboxylic acid 
• 1142225-04-4 4-(4-(chloromethyl)-2-(5,5-dimethylcyclopent-1-en-1-yl)phenyl)-5-fluoro-2-methoxypyridine 
• 1142224-55-2 (2-((1R)-2,2-dimethylcyclopentyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-yl)methanol 
• 1142224-53-0 (2-((1S)-2,2-dimethylcyclopentyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-yl)methanol 

Relevant articles and documents

Discovery of AM-1638: A potent and orally bioavailable GPR40/FFA1 full agonist

GPR40 (FFA1) is a G-protein-coupled receptor, primarily expressed in pancreatic islets, the activation of which elicits increased insulin secretion only in the presence of elevated glucose levels. A potent, orally bioavailable small molecule GPR40 agonist

SPIROCYCLIC GPR40 MODULATORS

The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula IA, IB, I'A or I'B, where the definitions of the variables are provided herein. The present invention also