114467-84-4Relevant academic research and scientific papers
Reactions of (chlorodifluoromethyl)benzene and (chlorodifluoromethoxy) benzene with nucleophilic reagents
Guidotti, Jér?me,Schanen, Vincent,Tordeux, Marc,Wakselman, Claude
, p. 445 - 449 (2005)
Condensation reactions of (chlorodifluoromethyl)benzene and (chlorodifluoromethoxy)benzene with phenoxide and thiophenoxide ions have been performed in DMF or NMP with heating. In these conditions, the reaction between phenylselenide ion and (chlorodifluo
A Convenient Synthesis of Difluoroalkyl Ethers from Thionoesters Using Silver(I) Fluoride
Newton, Josiah,Driedger, Daniel,Nodwell, Matthew B.,Schaffer, Paul,Martin, Rainer E.,Britton, Robert,Friesen, Chadron M.
supporting information, p. 15993 - 15997 (2019/11/19)
Herein we report the mild and rapid fluorodesulfurization of thionoesters using only silver(I) fluoride. This reaction demonstrates excellent functional group tolerance and complements existing strategies for difluoroalkyl ether synthesis, which rely on t
Fluorodecarboxylation: Synthesis of aryl trifluoromethyl ethers (ArOCF3) and thioethers (ArSCF3)
Krishanmoorthy, Sankarganesh,Schnell, Simon D.,Dang, Huong,Fu, Fang,Prakash, G.K. Surya
, p. 130 - 135 (2017/09/06)
Fluorodecarboxylation of aryloxydifluoroacetic acid (ArOCF2CO2H) and arylmercaptodifluoroacetic acid (ArSCF2CO2H) towards ArXCF3 (X = O, S) using silver (I) salts in the presence of Selectfluor in a biphasic system with trifluoroacetic acid additive is discussed.
Reaction of carbonyl compounds with xenon difluoride in the presence of silicon tetrafluoride
Tamura, Masanori,Matsukawa, Yasuhisa,Quan, Heng-Dao,Mizukado, Junji,Sekiya, Akira
, p. 705 - 709 (2007/10/03)
Reaction of various carbonyl compounds with xenon difluoride in the presence of silicon tetrafluoride was investigated. Aromatic aldehyde, ketones, and α-ketoester react with xenon difluoride to give α,α-difluoroalkyl phenyl ethers. However, acid fluoride, ester, acid cyanide, α-ketocarboxylic acid, or thioester do not afford the corresponding products. In the case of cinnamaldehyde, fluorination was accompanied by intramolecular cyclization to afford fluorinated epoxide.
Syntheses of New Aromatic Compounds with Fluorinated Side Chains and their Chemical Reactivity
Haas, Alois,Spitzer, Martin,Lieb, Max
, p. 1329 - 1340 (2007/10/02)
The syntheses of a wide range of aromatic compounds of the type p-Y-C6H4CF2X(4-13) are described, and the chemical behavior of these compounds as a function of substituent Y is investigated .Analogously the pyridine derivatives 15, 17, and 18 were synthesized and characterized.From a correlation of the 19F-NMR data of these compounds with the Hammett constant of Y, participation of C-F ?-back-donation is seen as the cause for an observed shift of the 19F signals to lower field.
