114531-89-4

Upstream product

• 78620-93-6 (+/-)-3-cyclohexyl-3-hydroxy-3-phenylpropanoic acid 
• 712-50-5 Cyclohexyl phenyl ketone 
• 105-36-2 ethyl bromoacetate 
• 26482-37-1 (+/-)-3-cyclohexyl-3-hydroxy-3-phenylpropanoic acid ethyl ester 

Downstream Products

• 114499-81-9 (S)-(+)-1-cyclohexyl-1-phenyl-1,3-propanediol 
• 135033-61-3 (S)-(+)-1-cyclohexyl-1-phenyl-2-propen-1-ol 
• 149598-04-9 (+)-(2S,3S)-trans-3-cyclohexyl-3-phenyloxiranemethanol 
• 149714-32-9 (2R,3S)-(+)-3-cyclohexyl-2,3-epoxy-3-phenyl-1-propanol 
• 149598-01-6 (1S,2S)-(+)-1-cyclohexyl-2,3-epoxy-1-phenyl-1-propanol 
• 149632-19-9 (1S,2R)-(+)-1-cyclohexyl-2,3-epoxy-1-phenyl-1-propanol 
• 149597-99-9 (S)-(+)-3-cyclohexyl-3-hydroxy-3-phenylpropyl 4-nitrobenzenesulfonate 
• 149598-05-0 (2S,3S)-(+)-3-cyclohexyl-2,3-epoxy-3-phenylpropyl 4-nitrobenzenesulfonate 
• 149714-35-2 (2R,3S)-(+)-3-cyclohexyl-2,3-epoxy-3-phenylpropyl 4-nitrobenzenesulfonate 
• 30953-86-7 (+)-Trihexyphenidyl hydrochloride 
• 30953-83-4 (S)-(+)-1-cyclohexyl-1-phenyl-3-(1-pyrrolidinyl)-1-propanol hydrochloride 
• 114499-82-0 (S)-(-)-3-chloro-1-cyclohexyl-1-phenyl-1-propanol 

Relevant academic research and scientific papers

Anticholinergic Agents 3. Synthesis and Configurational Assignment of the Four Stereoisomers of 1-Cyclohexyl-1,2-epoxy-1-phenyl-3-piperidinylpropane

The four stereoisomers of 1-cyclohexyl-1,2-epoxy-1-phenyl-3-piperidylpropane which are putative muscarinic antagonists, have been synthesised employing (S)- and (R)-1-cyclohexyl-1-phenyl-1,3-propanediol as chiral synthons.The relative configuration of the

Syntheses of (S)-(+)-trihexyphenidyl hydrochloride and (S)-(+)-procyclidine hydrochloride, two anticholinergics, using (S)-(-)-3-cyclohexyl-3-hydroxy-3-phenylpropanoic acid as chiral synthon.

The absolute configuration of the more active (-)-enantiomer of the anticholinergic trihexyphenidyl hydrochloride has been established as (R) by syntheses of (S)-(+)-procyclidine hydrochloride, whose absolute configuration has been established previously,