1146214-77-8

Basic information

• Product Name: Methyl 2-methoxy-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
• Synonyms: 3-Methoxy-2-(methoxycarbonyl)phenylboronic acid, pinacol ester;Methyl 2-methoxy-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate;Methyl 2-methoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
• CAS NO: 1146214-77-8
• Molecular Formula: C₁₅H₂₁BO₅
• Molecular Weight: 292.13524
• Mol File: 1146214-77-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Methyl 2-methoxy-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-methoxy-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate(1146214-77-8)
• EPA Substance Registry System: Methyl 2-methoxy-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate(1146214-77-8)

Safety Data

• Hazardous Substances Data: 1146214-77-8(Hazardous Substances Data)

Usage

General Description

Methyl 2-methoxy-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is a compound that belongs to the class of organic compounds known as benzoic acid esters. It is derived from benzoic acid and methanol and contains a boron atom within its structure. This chemical is commonly used as an intermediate in the production of pharmaceuticals, agrochemicals, and other organic compounds. It is also known for its potential application in organic synthesis due to the presence of the boron group, which can participate in various reactions such as Suzuki-Miyaura coupling, a widely utilized method for carbon-carbon bond formation in organic chemistry.

Upstream product

• 606-45-1 2-methoxybenzoic acid methyl ester 
• 73183-34-3 bis(pinacol)diborane 
• 31786-45-5 2-bromo-6-methoxybenzoic acid 
• 31786-46-6 methyl 2-bromo-6-methoxy-benzoate 

Downstream Products

• 128174-47-0 (E)-7-methoxy-3-styrylisobenzofuran-1(3H)-one 
• 54166-96-0 methyl 2-amino-6-methoxybenzoate 
• 22833-69-8 methyl 6-methoxysalicylate 
• 1379337-67-3 methyl 6-iodo-2-methoxybenzoate 
• 31786-46-6 methyl 2-bromo-6-methoxy-benzoate 
• 936479-46-8 methyl 6-chloro-2-methoxybenzoate 
• 178747-79-0 methyl 2-fluoro-6-methoxybenzoate 
• 1353055-85-2 methyl 2-methoxy-6-(phenylthio)benzoate 

Relevant articles and documents

Synthesis of thioxanthones through formal C-H thiolation of benzoic acid esters and Acid-mediated Direct Cyclization

An efficient thioxanthone synthesis from benzoic acid esters is disclosed. Various thioxanthones were prepared by iridiumcatalyzed C-H borylation of benzoic acid esters followed by copper-catalyzed deborylthiolation and direct acid-mediated cyclization. We also achieved a synthesis of benzo-fused thioxanthones through a transformation of an aryne intermediate having an ester moiety.

Selenium-catalyzed C(sp3)-H acyloxylation: Application in the expedient synthesis of isobenzofuranones

Oxidative Se-catalyzed C(sp3)-H bond acyloxylation has been used to construct a diverse array of isobenzofuranones from simple ortho-allyl benzoic acid derivatives. The synthetic procedure employs mild reaction conditions and gives high chemoselectivity enabled by an inexpensive organodiselane catalyst. The presented approach offers a new synthetic pathway toward the core structures of phthalide natural products.

Directed ortho borylation of functionalized Arenes catalyzed by a silica-supported compact phosphine-iridium system

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