31786-46-6

Usage

Uses

Used in Pharmaceutical Industry:
Methyl 2-bromo-6-methoxybenzoate is used as a reactant for the synthesis of orchid pigments, specifically dengibsin and dengibsinin. These pigments are of interest due to their potential applications in the pharmaceutical industry, possibly for the development of novel drugs or as markers in biological research.
Used in Chemical Synthesis:
Methyl 2-bromo-6-methoxybenzoate is used as an intermediate in the synthesis of various organic compounds, particularly those with potential applications in the pharmaceutical, agrochemical, and materials science industries. Its unique structure and reactivity make it a versatile building block for the creation of new molecules with specific properties and functions.

Upstream product

• 606-45-1 2-methoxybenzoic acid methyl ester 
• 1146214-77-8 2-methoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester 
• 67-56-1 methanol 
• 31786-45-5 2-bromo-6-methoxybenzoic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 74-88-4 methyl iodide 

Downstream Products

• 128174-47-0 (E)-7-methoxy-3-styrylisobenzofuran-1(3H)-one 
• 1146214-77-8 2-methoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester 
• 921207-63-8 methyl 2-methoxy-6-vinylbenzoate 
• 80241-82-3 methyl 2-formyl-6-methoxybenzoate 

Relevant academic research and scientific papers

N,B-bidentate boryl ligand-supported iridium catalyst for efficient functional-group-directed C-H borylation

Convenient silylborane precursors for introducing N,B-bidentate boryl ligands onto transition metals were designed, prepared, and employed in ready formation of irdium(IIl) complexes via Si-B oxidative addition. A practical, efficient catalytic ortho-borylation reaction of arenes with a broad range of directing groups was developed using an in situ generated catalyst from the silylborane preligand 3c and [IrCl(COD)]2.

Selenium-catalyzed C(sp3)-H acyloxylation: Application in the expedient synthesis of isobenzofuranones

Oxidative Se-catalyzed C(sp3)-H bond acyloxylation has been used to construct a diverse array of isobenzofuranones from simple ortho-allyl benzoic acid derivatives. The synthetic procedure employs mild reaction conditions and gives high chemoselectivity enabled by an inexpensive organodiselane catalyst. The presented approach offers a new synthetic pathway toward the core structures of phthalide natural products.

PYRIDINYL AND FUSED PYRIDINYL TRIAZOLONE DERIVATIVES

Disclosed are compounds of Formula 1, or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, and R4 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating Type I hypersensitivity reactions, autoimmune diseases, inflammatory disorders, cancer, non-malignant proliferative disorders, and other conditions associated with BTK.