114679-00-4Relevant articles and documents
Palladium-Catalyzed Chemo- and Enantioselective C?O Bond Cleavage of α-Acyloxy Ketones by Hydrogenolysis
Chen, Jianzhong,Zhang, Zhenfeng,Liu, Delong,Zhang, Wanbin
supporting information, p. 8444 - 8447 (2016/07/19)
A chemoselective C?O bond cleavage of the ester alkyl side-chain of α-acyloxy ketones was realized for the first time by a highly efficient palladium-catalyzed hydrogenolysis (S/C=6000, the highest catalytic efficiency by far). Furthermore, a kinetic resolution of α-acyloxy ketones was first developed by enantioselective hydrogenolysis with good yields and up to 99 % ee.
One-pot, two-step desymmetrization of symmetrical benzils catalyzed by the methylsulfinyl (dimsyl) anion
Ragno, Daniele,Bortolini, Olga,Giovannini, Pier Paolo,Massi, Alessandro,Pacifico, Salvatore,Zaghi, Anna
, p. 5733 - 5744 (2014/07/22)
An operationally simple one-pot, two-step procedure for the desymmetrization of benzils is herein described. This consists in the chemoselective cross-benzoin reaction of symmetrical benzils with aromatic aldehydes catalyzed by the methyl sulfinyl (dimsyl) anion, followed by microwave-assisted oxidation of the resulting benzoylated benzoins with nitrate, avoiding the costly isolation procedure. Both electron-withdrawing and electron-donating substituents may be accommodated on the aromatic rings of the final unsymmetrical benzil. the Partner Organisations 2014.
A New Site Selective Synthesis of Benzoin Esters. Synthesis of Symmetrically and Unsymmetrically Substituted Benzils
Armesto, Diego,Horspool, William M.,Ortiz, Maria J.,Perez-Ossorio, Rafael
, p. 799 - 801 (2007/10/02)
A series of novel benzoin esters has been obtained in high yield, in a site selective synthesis, by the acid hydrolysis of a series of 4-benzoyloxy-2-azabuta-1,3-dienes.The oxidation of the benzoin esters allows the preparation of symmetrically and unsymmetrically substituted benzils by a route that is superior, in some cases, to those previously reported.
