115014-77-2

Usage

Chemical Properties

WHITE CRYSTALLINE POWDER

InChI:InChI=1/C7H14N2O/c8-6-4-2-1-3-5(6)7(9)10/h5-6H,1-4,8H2,(H2,9,10)

Upstream product

• 22031-53-4 cis-2-aza-3-oxobicyclo<4.2.0>octane 
• 371-27-7 2,2,2-trifluoroethylbutyrate 
• 110901-40-1 trans-2-aminocyclohexane-1-carboxamide 
• 24717-01-9 cis-2-aminocyclohexane-1-carboxamide 
• 161618-52-6 cis-2-aminocyclohexanecarboxylic acid methyl ester 
• 503167-50-8 (1S,2R)-2-amino-cyclohexanecarboxylic acid methyl ester 
• 110-83-8 cyclohexene 
• 24716-92-5 (±)-cis-2-aminocyclohexane-1-carboxylic acid hydrochloride 
• 202867-96-7 2-benzyloxycarbonylamino-cyclohexanecarboxylic acid 
• 61935-48-6 trans-2-(benzyloxycarbonylamino)cyclohexanecarboxylic acid 
• 5691-19-0 trans-2-amino-1-cyclohexanecarboxylic acid 
• 132724-02-8 trans-2-(benzyloxycarbonylamino)cyclohexanecarboxamide 
• 1436-60-8 ethyl cis-2-amino-1-cyclohexanecarboxylate 
• 54867-08-2 cis-2-(benzyloxycarbonylamino)cyclohexanecarboxylic acid 

Downstream Products

• 1123-97-3 4,5,6,7-Tetrahydrobenzimidazolidin-2-one 
• 96058-39-8 2,3-diphenyl-4a,5,6,7,8,8a-hexahydroquinoxaline 
• 155856-84-1 (2-amino-cyclohexyl)-carbamic acid 
• 98692-01-4 N,N'-cyclohexane-1,2-diyl-bis-benzenesulfonamide 
• 111302-94-4 (1S,2S)-2-sec-Butylamino-cyclohexanecarboxylic acid amide 
• 26853-51-0 (1S,2S)-1-amino-2-aminomethylcyclohexane 
• 91972-78-0 2-cyclohexylaminocyclohexanecarboxaamide 
• 111302-92-2 (1S,2S)-2-Isopropylamino-cyclohexanecarboxylic acid methylamide 
• 111302-91-1 (1S,2S)-2-Isopropylamino-cyclohexanecarboxylic acid amide 
• 114950-64-0 (r-4a,t-2,c-8a)-2-p-nitrophenylperhydroquinazolin-4-one 
• 114950-66-2 (1R,2S)-2-{[1-(4-Nitro-phenyl)-meth-(E)-ylidene]-amino}-cyclohexanecarboxylic acid amide 
• 114950-64-0 (r-4a,t-2,t-8a)-2-p-nitrophenylperhydroquinazolin-4-one 
• 114950-66-2 (1S,2S)-2-{[1-(4-Nitro-phenyl)-meth-(E)-ylidene]-amino}-cyclohexanecarboxylic acid amide 
• 111302-95-5 (1S,2S)-2-(4-Chloro-benzylamino)-cyclohexanecarboxylic acid amide 

Relevant academic research and scientific papers

Lipase-catalyzed kinetic resolution of 2-aminocyclopentane- and 2-aminocyclohexanecarboxamides

Candida antarctica lipase B (CAL-B)-catalyzed N-acylation with 2,2,2-trifluoroethyl butanoate in solvent mixtures of tert-butyl methyl ether and tert-amyl alcohol was used to prepare all the enantiomers of cis- and trans-2-aminocyclopentane- and -cyclohexanecarboxamides. An unexpected change in enantiopreference, accompanied by low enantioselectivity, was observed when Pseudomonas cepacia lipase (cis-cyclohexane substrate) or C. antarctica lipase A (cis-cyclopentane and -cyclohexane substrates) replaced CAL-B.

Antiamyloid phenylsulfonamides: N-cycloalkylcarboxamides derivatives

A series of N-cycloalkylcarboxamide derivatives of N-benzyl benzenesulfonamides of Formula I are described. The compounds inhibit β-amyloid peptide (β-AP) production and are useful in the treatment of Alzheimer's Disease and other conditions characterized

Structure-based design and synthesis of phosphinate isosteres of phosphotyrosine for incorporation in Grb2-SH2 domain inhibitors. Part 1

Based on X-ray crystal structure information, mono charged phosphinate isosteres of phosphotyrosine have been designed and incorporated in a short inhibitory peptide sequence of the Grb2-SH2 domain. The resulting compounds, by exploiting additional interactions, inhibit binding to the Grb2-SH2 domain as potently as the corresponding doubly charged (phosphonomethyl)phenylalanine analogue. (C) 2000 Elsevier Science Ltd.

An Efficient Synthesis of cis- and trans-2-Aminocyclohexanecarboxamides and Their N-Substituted Derivatives

In this paper we describe a new approach to cis- and trans-2-aminocyclohexanecarboxamides and their N-substituted derivatives, which proceeds much faster and in higher yields than the methods described in the literature and usually employed in peptide che

5,6-Dihydropyrimidin-4(3H)one derivatives, and antiedema compositions and methods employing them

An antiedema compound of the formula: STR1 in which R1 is methyl, ethyl, cyclohexyl, phenyl, m-tolyl, p-tolyl, p-tert-butylphenyl, m-trifluoromethylphenyl, m-fluorophenyl, p-fluorophenyl, m-chlorophenyl, p-chlorophenyl, m-bromophenyl, p-bromoph