115236-89-0

Upstream product

• 108-24-7 acetic anhydride 
• 6022-96-4 5-O-benzoyl-α-D-xylofuranose 
• 6612-91-5 ((3aR,5R,65,6aR)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methyl benzoate 
• 98-88-4 benzoyl chloride 
• 20031-21-4 1,2-O-isopropylidene-α-D-xylose 

Downstream Products

• 190003-78-2 1-(2',3'-di-O-acetyl-5'-O-benzoyl-β-D-xylofuranosyl)thymine 
• 115269-14-2 Benzoic acid (2R,3R,4S,5S)-3,4,5-triacetoxy-tetrahydro-furan-2-ylmethyl ester 
• 115269-13-1 Benzoic acid (2R,3R,4S,5R)-3,4,5-triacetoxy-tetrahydro-furan-2-ylmethyl ester 
• 115269-11-9 1,2,3-tri-O-acetyl-5-O-benzoyl-β-D-ribofuranose 
• 115269-12-0 Benzoic acid (2R,3R,4R,5R)-3,4,5-triacetoxy-tetrahydro-furan-2-ylmethyl ester 
• 190003-84-0 1-(5'-O-benzoyl-2',3'-di-O-methylsulfonyl-β-D-xylofuranosyl)thymine 
• 190003-86-2 2,2'-anhydro-1-(5'-O-benzoyl-3'-O-methylsulfonyl-β-D-lyxofuranosyl)thymine 
• 190003-85-1 Benzoic acid (2R,3S,4R,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3,4-bis-(toluene-4-sulfonyloxy)-tetrahydro-furan-2-ylmethyl ester 
• 190003-80-6 1-(5'-O-benzoyl-β-D-xylofuranosyl)thymine 
• 3056-17-5 stavudin 
• 122567-97-9 5′-benzoyl-2′,3′-didehydro-3′-deoxythymidine 

Relevant academic research and scientific papers

Transformations of β-D-Xylofuranosyl Nucleosides. Synthesis of 3′-Deoxy-2′,3′-didehydrothymidine (D4T)

3′-Deoxy-2′,3′-didehydrothymidine was synthesized through a 10-step procedure starting from D-xylose. The overall yield of the target product was 28%.

EPIMERIZATION DURING THE ACETOLYSIS OF 3-O-ACETYL-5-O-BENZOYL-1,2-O-ISOPROPYLIDENE-3-C-METHYL-α-D-RIBOFURANOSE. SYNTHESIS OF 3'-C-METHYLNUCLEOSIDES WITH THE β-D-ribo- AND α-D-arabino CONFIGURATIONS

Acetolysis of 3-O-acetyl-5-O-benzoyl-1,2-O-isopropylidene-3-C-methyl-α-D-ribofuranose with a high concentration of acetic acid yielded 1,2,3-tri-O-acetyl-5-O-benzoyl-3-C-methyl-D-arabinofuranose, which was used for the preparation of 3-C-methyl-α-D-arabinofuranosyl nucleosides. 3'-C-Methylribonucleosides were also synthesized starting from 1,2,3-tri-O-acetyl-5-O-benzoyl-3-C-C-methyl-D-ribofuranose.