115463-41-7Relevant academic research and scientific papers
Synthesis of Medium-Sized Carbocycles by Gallium-Catalyzed Tandem Carbonyl-Olefin Metathesis/Transfer Hydrogenation
Djurovic, Alexandre,Vayer, Marie,Li, Zhilong,Guillot, Regis,Baltaze, Jean-Pierre,Gandon, Vincent,Bour, Christophe
, p. 8132 - 8137 (2019/10/14)
The first examples of a catalytic tandem process involving a ring-closing carbonyl-olefin metathesis and a transfer hydrogenation are described. 1,4-Cyclohexadiene has been used as an H2 surrogate to reduce the cyclic alkenes formed after the m
Chiral hetero- and carbocyclic compounds from the asymmetric hydrogenation of cyclic alkenes
Verendel, J. Johan,Li, Jia-Qi,Quan, Xu,Peters, Byron,Zhou, Taigang,Gautun, Odd R.,Govender, Thavendran,Andersson, Pher G.
, p. 6507 - 6513 (2012/06/29)
Several types of chiral hetero- and carbocyclic compounds have been synthesized by using the asymmetric hydrogenation of cyclic alkenes. N,P-Ligated iridium catalysts reduced six-membered cyclic alkenes with various substituents and heterofunctionality in good to excellent enantioselectivity, whereas the reduction of five-membered cyclic alkenes was generally less selective, giving modest enantiomeric excesses. The stereoselectivity of the hydrogenation depended more strongly on the substrate structure for the five- rather than the six-membered cyclic alkenes. The major enantiomer formed in the reduction of six-membered alkenes could be predicted from a selectivity model and isomeric alkenes had complementary enantioselectivity, giving opposite optical isomers upon hydrogenation. The utility of the reaction was demonstrated by using it as a key step in the preparation of chiral 1,3-cis-cyclohexane carboxylates. Copyright
Radical translocation reactions of vinyl radicals: Substituent effects on 1,5-hydrogen-transfer reactions
Curran, Dennis P.,Shen, Wang
, p. 6051 - 6059 (2007/10/02)
A systematic study of the radical translocation (1,5-hydrogen-transfer) reactions of vinyl radicals is described. The effects of monoalkoxy, dialkoxy, monoalkylthio, dialkylthio, thiohemiketal, phenyl, allyl, carboxylate ester, nitrile, and tertiary, seco
Atom Transfer Addition and Annulation Reactions of Iodomalonates
Curran, Dennis P.,Chen, Meng-Hsin,Spletzer, Eric,Seong, Churl Min,Chang, Chi-Tai
, p. 8872 - 8878 (2007/10/02)
Atom transfer addition and annulation reactions of iodomalonates with alkyl- and phenyl-substituted alkenes are described.For example, sunlamp irradiation of dimethyl methyliodomalonate and 1-hexene in the presence of 10percent hexabutylditin provides dim
