116707-97-2

Basic information

• Product Name: N-(2-bromo-4-methoxyphenyl)acrylamide
• Synonyms: N-(2-bromo-4-methoxyphenyl)acrylamide
• CAS NO: 116707-97-2
• Molecular Weight: 256.099
• Mol File: 116707-97-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(2-bromo-4-methoxyphenyl)acrylamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-bromo-4-methoxyphenyl)acrylamide(116707-97-2)
• EPA Substance Registry System: N-(2-bromo-4-methoxyphenyl)acrylamide(116707-97-2)

Safety Data

• Hazardous Substances Data: 116707-97-2(Hazardous Substances Data)

Upstream product

• 32338-02-6 2-bromo-4-methoxyaniline 
• 79-10-7 acrylic acid 
• 814-68-6 acryloyl chloride 
• 591-20-8 3-Bromophenol 
• 98447-30-4 2-bromo-4-methoxy-1-nitrobenzene 
• 5470-65-5 3-bromo-4-nitrophenol 

Downstream Products

• 7766-37-2 N-(4-methoxyphenyl)acrylamide 
• 444166-96-5 N-(2-bromo-4-methoxyphenyl)-N-(2-trimethylsilylethoxymethyl)acrylamide 
• 116707-99-4 1,3-dimethyl-5-methoxyindolin-2-one 
• 324520-90-3 3-[(2-bromo-4-methoxy-phenyl)-(2-trimethylsilanyl-ethoxymethyl)-carbamoyl]-pyrrole-1-carboxylic acid methyl ester 
• 324520-82-3 1H-pyrrole-3-carboxylic acid (2-bromo-4-methoxy-phenyl)-(2-trimethylsilanyl-ethoxymethyl)-amide 
• 324520-93-6 1-methyl-1H-pyrrole-3-carboxylic acid (2-bromo-4-methoxy-phenyl)-(2-trimethylsilanyl-ethoxymethyl)-amide 
• 324520-87-8 3-[(2-bromo-4-methoxy-phenyl)-methyl-carbamoyl]-pyrrole-1-carboxylic acid tert-butyl ester 
• 324520-81-2 N-(2-bromo-4-methoxyphenyl)-N-methyl-1H-3-pyrrolecarboxamide 
• 116707-98-3 N-(2-bromo-4-methoxyphenyl)-N-methylacrylamide 

Relevant articles and documents

A formal total synthesis of geneserine

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Aryl radical cyclisation onto pyrroles

The intramolecular cyclisation of aryl radicals onto a pyrrole is studied. The cyclisation allows the synthesis of either the spiropyrrolidinyloxindole or the pyrrolo[3,2-c]quinoline skeleton depending on the nature of the protecting group at the N-pyrrole atom. The regiochemistry of the cyclisation is not affected by the substituents on the benzene ring. Some limitations on the utility of tosylmethylisocyanide in pyrrole synthesis are also reported.