116834-99-2

Upstream product

• 75594-91-1 C₁₈H₁₅N₃ 
• 5424-19-1 3-Benzoylpyridine 
• 100-63-0 phenylhydrazine 
• 72583-84-7 1-phenyl-1H-pyrazolo[3,4-b]pyridin-3-amine 
• 6602-54-6 2-chloro-3-pyridinecarbonitrile 
• 685522-75-2 3-iodo-1-phenyl-1H-pyrazolo[3,4-b]pyridine 
• 98-80-6 phenylboronic acid 
• 102-52-3 malonaldehydebis(dimethylacetal) 
• 5356-71-8 1,3-diphenyl-1H-pyrazol-5-amine 

Relevant academic research and scientific papers

Synthesis of indazoles and azaindazoles by intramolecular aerobic oxidative C-N coupling under transition-metal-free conditions

A transition-metal-free oxidative C-N coupling method has been developed for the synthesis of 1H-azaindazoles and 1H-indazoles from easily accessible hydrazones. The procedure uses TEMPO, a basic additive, and dioxygen gas as the terminal oxidant. This reaction demonstrates better reactivity, functional group tolerance, and broader scope than comparable metal catalyzed reactions. A transition-metal-free oxidative C-N coupling method has been developed for the synthesis of 1H-azaindazoles and 1H-indazoles from easily accessible hydrazones (see scheme). The procedure uses TEMPO, a basic additive, and dioxygen gas as the terminal oxidant. This reaction demonstrates better reactivity, functional group tolerance, and broader scope than comparable metal catalyzed reactions. TEMPO=2,2,6,6-tetramethyl-1-piperidinyloxy.

Synthesis and functionalisation of 1H-pyrazolo[3,4-b]pyridines involving copper and palladium-promoted coupling reactions

A convenient route to novel 3-iodo-1H-pyrazolo[3,4-b]pyridines via iododediazonation of 3-amino-1H-pyrazolo[3,4-b]pyridines, which are obtained by copper-catalysed cyclisation of 2-chloro-3-cyanopyridine with hydrazines. We describe also efficient couplin