116855-48-2

Upstream product

• 20781-86-6 N-(2,6-diisopropylphenyl)-2-chloroacetamide 
• 109-89-7 diethylamine 
• 24544-04-5 2,6-diisopropylbenzenamine 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 116855-34-6 N-<2-(diethylamino)ethyl>-N-<2,6-bis(1-methylethyl)phenyl>-4-<(methylsulfonyl)amino>benzamide 
• 116855-49-3 N,N-diethyl-N'-<2,6-bis(1-methylethyl)phenyl>-1,2-ethanediamine 

Relevant academic research and scientific papers

N-(aminoalkyl)-substituted(N or C alkyl)-aryl-4(methylsulfonylamino)benzamides

N-(aminoalkyl)-substituted(N or C alkyl)-aryl-4-(methylsylfonylamino)benzamides of the formula STR1 wherein R is C1 -C4 straight chain alkyl, one of R1, R2 and R3 is a phenyl or naphthyl group and the others are hydrogen, --NR4 R5 is a secondary or teritary amino group, X and X1 are hydrogen or alkyl and n is 0 or 1, are useful as antiarrhythmic agents in the treatment of cardiac arrhythmias especially as combination Class I/Class III agents.

Synthesis and Cardiac Electrophysiological Activity of Aryl-Substituted Derivatives of the Class III Antiarrhythmic Agent Sematilide. Potential Class I/III Agents

Twelve novel derivatives of the selective class III antiarrhythmic agent sematilide were prepared in an attempt to incorporate both class I and class III electrophysiological properties into a single molecule.Electrophysiological activity was determined b