117680-17-8

Basic information

• Product Name: 2-(IODOMETHYL)FURAN
• Synonyms: 2-(IODOMETHYL)FURAN
• CAS NO: 117680-17-8
• Molecular Formula: C₅H₅IO
• Molecular Weight: 208
• Mol File: 117680-17-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 195.8 °C at 760 mmHg
• Flash Point: 72.2 °C
• Appearance: /
• Density: 1.937 g/cm³
• Vapor Pressure: 0.576mmHg at 25°C
• Refractive Index: 1.594
• CAS DataBase Reference: 2-(IODOMETHYL)FURAN(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(IODOMETHYL)FURAN(117680-17-8)
• EPA Substance Registry System: 2-(IODOMETHYL)FURAN(117680-17-8)

Safety Data

• Hazardous Substances Data: 117680-17-8(Hazardous Substances Data)

Usage

General Description

2-(Iodomethyl)Furan, also known as IMDM, is a chemical compound that consists of a furan ring with an attached iodomethyl group. It is commonly used as a chemical building block in organic synthesis and pharmaceutical research. IMDM is often utilized as a reagent in the preparation of various organic compounds, including pharmaceuticals, agrochemicals, and materials. It has also been studied for its potential use in the development of novel drugs and biologically active molecules. Additionally, IMDM can be used as a ligand in metal-catalyzed reactions and as a precursor for the synthesis of heterocyclic compounds. Due to its versatile reactivity and synthetic applications, 2-(Iodomethyl)Furan is a valuable tool for chemical research and drug discovery efforts.

InChI:InChI=1/C5H5IO/c6-4-5-2-1-3-7-5/h1-3H,4H2

Upstream product

• 98-00-0 (2-furyl)methyl alcohol 
• 92785-12-1 Co(ONC(CH₃)C(CH₃)NOH)2(pyridine)(furfuryl) 
• 7553-56-2 iodine 
• 7790-99-0 Iodine monochloride 
• 145147-96-2 3-(4-penten-1-yloxy)propanoic acid 

Downstream Products

• 4437-22-3 2,2-[oxybis(methylene)]bis-furan 
• 13679-46-4 2-(methoxymethyl)furan 
• 6270-56-0 2-(ethoxymethyl)furan 
• 534-22-5 2-methylfuran 
• 98-01-1 furfural 

Relevant articles and documents

Oxygen Effect in the Iodo Lactonization of Unsaturated Carboxylic Acids Leading to 7- to 12-Membered Ring Lactones

The reaction of ω-alkenoic acids with bis(sym-collidine)iodine(I) hexafluorophosphate led to (iodomethyl) ε-caprolactones in good yields (49-75percent) and medium ring iodo lactones in low yields (4-5percent).The latter compounds have been obtained after introduction of an oxygen atom in the carbon chain.The position of the oxygen appeared important.This oxygen effect was explained by the stabilization of the intermediate iodonium ion by the oxygen atom.

An efficient and selective method for the iodination and bromination of alcohols under mild conditions

A straightforward and effective procedure for the conversion of a variety of alcohols into the corresponding alkyl iodides and bromides is described using KX/P2O5 (X = I, Br). The reactions were easily carried out in acetonitrile under mild conditions. Using this method, the selective conversion of benzylic alcohols in the presence of aliphatic alcohols was achieved.

NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVE AND A PRODUCTION METHOD FOR SAME

The present invention relates to a pyrrolopyridine derivative represented by the Chemical Formula I, and a racemate or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and relates to an antiviral composition including the same as an active ingredient. The compound of the Chemical Formula I has excellent antiviral activity and selectivity for wild type and resistant HIV-1, and thereby is useful as a therapeutic agent for acquired immune deficiency syndrome (AIDS).