1178-24-1Relevant articles and documents
Isolation and Characterization of an Antibacterial Substance from Citrus Plant
Ito, Chihiro,Fujiwara, Kazuko,Koizumi, Meisaku,Furukawa, Hiroshi
, p. 89 - 91 (1998)
Citrus bacterial canker caused by Xanthomomas campestris pv. citri (Hasse 1915) Dye 1978, a gram-negative and rod-shape bacteria, is one of the destructive diseases of Citrus. There is marked diversity in resistance to the disease among Citrus plants. Calamondin, Citrus madurensis Lour. (Shiki-kitsu) is one of the highly resistant plants.1 In resistant plants bacterial multiplication is restrained by the embedding of electron dense materials in intercellular spaces.2 This suggests the presence of an antibacterial substance in resistant plants. The third author assayed the 85% ethanol extracts of Citrus leaves infected with bacterial canker for static activities to X. campestris. pv. citri. An active fraction was found in Calamondin. We further purified and characterized its ingredients on the basis of spectrometric analyses. Its structure was found to be identical with 3-hydroxy-5,6,7,8,3′,4′-hexamethoxyflavone (1) isolated from Citrus natsudaidai Hayata. However, its antibacterial activity is first reported by us.
Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs
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Page/Page column 37, (2017/07/01)
Disclosed is a use of flavones derivatives and flavanone derivatives in preparation of sedative and hypnotic drugs.
Regioselective hydroxylation of 2-hydroxychalcones by dimethyldioxirane towards polymethoxylated flavonoids
Chu, Han-Wei,Wu, Huan-Ting,Lee, Yean-Jang
, p. 2647 - 2655 (2007/10/03)
The flavone nucleus is part of a large number of natural products and medicinal compounds. In this presentation the novel regioselective hydroxylation of hydroxyarenes with DMD is described. The results showed further that flavonoids with 5-hydroxy group were selectively oxyfunctionalized at the para-position C8 carbon atom by DMD. Finally, according to this methodology, the naturally occurring isosinensetin, tangeretin, sinensetin, nobiletin, natsudaidain, gardenin B, 3,3′,4′,5,6,7,8- heptamethoxyflavone, quercetin and its derivatives were synthesized.