10544-05-5

Usage

Uses

Used in Pharmaceutical Industry:
4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-7-hydroxy-5-methoxyis used as a therapeutic agent for its antioxidant and anti-inflammatory properties, targeting various medical conditions that benefit from these effects.
Used in Nutraceutical Industry:
4H-1-Benzopyran-4-one,
2-(3,4-dimethoxyphenyl)-7-hydroxy-5-methoxyis used as a dietary supplement or functional food ingredient to provide health benefits, such as reducing inflammation and oxidative stress, and promoting overall well-being.
Used in Antioxidant Applications:
4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-7-hydroxy-5-methoxyis employed as an antioxidant, protecting cells from damage caused by reactive oxygen species and reducing the risk of chronic diseases associated with oxidative stress.
Used in Anti-Inflammatory Applications:
4H-1-Benzopyran-4-one,
2-(3,4-dimethoxyphenyl)-7-hydroxy-5-methoxyis used to reduce inflammation and alleviate symptoms in conditions such as arthritis, asthma, and inflammatory bowel disease, where its anti-inflammatory properties can provide relief and improve quality of life.

Upstream product

• 33554-52-8 3′-hydroxy-5,7,4′-trimethoxyflavone 
• 77-78-1 dimethyl sulfate 
• 520-27-4 diosmin 
• 742077-30-1 7-benzyloxy-2-(3,4-dimethoxy-phenyl)-5-hydroxy-chromen-4-one 
• 4712-12-3 5,7-dihydroxy-3',4'-dimethoxy flavone 
• 24824-54-2 3,4-dimethoxybenzoic anhydride 
• 72629-61-9 Luteolin-5,4'-dimethylether 
• 62346-14-9 7,4′-dihydroxy-5,3′-dimethoxyflavone 
• 2174-64-3 5-methoxyresorcinol 
• 4687-37-0 ethyl 3,4-dimethoxybenzoylacetate 
• 203191-62-2 7-benzyloxy-2-(3,4-dimethoxy-phenyl)-5-methoxy-chromen-4-one 

Downstream Products

• 203191-36-0 7-hydroxyethyloxy-3',4',5-trimethoxy flavone 
• 2174-59-6 5-hydroxy-6,7,8,3',4'-pentamethoxyflavone 
• 35154-55-3 3-hydroxy-5,6,7,8,3′,4′-hexamethoxyflavone 
• 1178-24-1 3,3',4',5,6,7,8-heptamethoxyflavone 
• 1176-88-1 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone 
• 478-01-3 nobiletin 
• 1092093-65-6 7-{(hydrophosphoryl)-methyloxy}-3',4',5-trimethoxyflavone 
• 1092093-75-8 7-{(diisopropylphosphoryl)-methyloxy}-3',4',5-trimethoxyflavone 
• 94550-33-1 7-acetoxy-2-(3,4-dimethoxy-phenyl)-5-methoxy-chromen-4-one 
• 491-70-3 2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on 
• 62346-14-9 7,4′-dihydroxy-5,3′-dimethoxyflavone 
• 72629-61-9 Luteolin-5,4'-dimethylether 
• 4712-12-3 5,7-dihydroxy-3',4'-dimethoxy flavone 
• 29080-58-8 5-hydroxy-3',4',7-trimethoxyflavone 

Relevant academic research and scientific papers

Synthesis of Citrus polymethoxyflavonoids and their antiproliferative activities on Hela cells

Abstract: A series of polymethoxyflavonoids (3–16) were synthesized through dehydrogenation, O-methylation, glycoside hydrolysis, bromination, microwave-assisted aromatic nucleophilic substitution, dimethyldioxirane oxidation and regioselective demethylation, starting from abundant and inexpensive natural sources naringin and hesperidin. All the synthetic compounds were test for antiproliferative activities on human cervical carcinoma Hela cell line by the standard CCK-8 assay, the result showed that most of the target compounds exhibited moderate to potent antiproliferative activities on Hela cells comparable with the positive control cis-Platin. Among them, 5-hydroxypolymethoxy flavonoid 13 showed the strongest activity (IC50 0.791 μM). Graphical Abstract: [InlineMediaObject not available: see fulltext.].

Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs

Disclosed is a use of flavones derivatives and flavanone derivatives in preparation of sedative and hypnotic drugs.

USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS

Disclosed is a use of flavones derivatives and flavanone derivatives in preparation of sedative and hypnotic drugs.

Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease

PCT No. PCT/KR97/00144 Sec. 371 Date Jan. 14, 1999 Sec. 102(e) Date Jan. 14, 1999 PCT Filed Jul. 25, 1997 PCT Pub. No. WO98/04541 PCT Pub. Date Feb. 5, 1998The present invention relates to novel flavone/flavanone compounds or their pharmaceutically acceptable salts and process for preparation thereof for protecting gastrointestinal tracts against gastritis, ulcers and inflammatory bowel disease.

On a Thermal Transmethylation Reaction with Flavon-5-methylethers

Upon heating to 300 deg C partial luteolinemethylethers undergo transmethylation.A reaction mechanism is put foreward. - Key words: Flavonemethylethers, Thermal Transmethylation, TLC, HPLC, Reaction Mechanism

CHRYSOERIOL 7-(2''-O-β-D-ALLOPYRANOSYL)-β-D-GLUCOPYRANOSIDE FROM SIDERITIS GRANDIFLORA

The aerial parts of Sideritis grandiflora yielded a new flavone glycoside, identified as chrysoeriol 7-(2''-allosylglucoside).Key Word Index - Sideritis grandiflora; Labiatae; 13C-NMR; chrysoeriol 7-(2''-O-β-D-allopyranosyl-β-D-glucopyranoside)