1187-99-1 Usage
Chemical Properties
Off-White Solid
Uses
Different sources of media describe the Uses of 1187-99-1 differently. You can refer to the following data:
1. A 4-substituted analog of Glutamic acid
2. A 4-substituted analog of Glutamic acid. This compound is a good enzyme substrate for GOT (glutamic oxalacetic aminotransferase).
Definition
ChEBI: An oxo dicarboxylic acid comprising glutaric acid having oxo- and hydroxy substituents at the 2- and 4-positions respectively.
Check Digit Verification of cas no
The CAS Registry Mumber 1187-99-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,8 and 7 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1187-99:
(6*1)+(5*1)+(4*8)+(3*7)+(2*9)+(1*9)=91
91 % 10 = 1
So 1187-99-1 is a valid CAS Registry Number.
InChI:InChI=1/C5H6O6/c6-2(4(8)9)1-3(7)5(10)11/h2,6H,1H2,(H,8,9)(H,10,11)
1187-99-1Relevant articles and documents
Stereoselective synthesis of γ-hydroxy-α-amino acids through aldolase-transaminase recycling cascades
Guérard-Hélaine, Christine,Heuson, Egon,Ndiaye, Moussa,Gourbeyre, Léa,Lemaire, Marielle,Hélaine, Virgil,Charmantray, Franck,Petit, Jean-Louis,Salanoubat, Marcel,De Berardinis, Véronique,Gefflaut, Thierry
supporting information, p. 5465 - 5468 (2017/07/06)
Efficient bi-enzymatic cascades combining aldolases and α-transaminases were designed for the synthesis of γ-hydroxy-α-amino acids. These recycling cascades provide high stereoselectivity, atom economy, and an equilibrium shift of the transamination. l-syn or anti-4-hydroxyglutamic acid and d-anti-4,5-dihydroxynorvaline were thus prepared in 83-95% yield in one step from simple substrates.