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1187-99-1

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1187-99-1 Usage

Chemical Properties

Off-White Solid

Uses

Different sources of media describe the Uses of 1187-99-1 differently. You can refer to the following data:
1. A 4-substituted analog of Glutamic acid
2. A 4-substituted analog of Glutamic acid. This compound is a good enzyme substrate for GOT (glutamic oxalacetic aminotransferase).

Definition

ChEBI: An oxo dicarboxylic acid comprising glutaric acid having oxo- and hydroxy substituents at the 2- and 4-positions respectively.

Check Digit Verification of cas no

The CAS Registry Mumber 1187-99-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,8 and 7 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1187-99:
(6*1)+(5*1)+(4*8)+(3*7)+(2*9)+(1*9)=91
91 % 10 = 1
So 1187-99-1 is a valid CAS Registry Number.
InChI:InChI=1/C5H6O6/c6-2(4(8)9)1-3(7)5(10)11/h2,6H,1H2,(H,8,9)(H,10,11)

1187-99-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-hydroxy-2-oxoglutaric acid

1.2 Other means of identification

Product number -
Other names 4-Hydroxy-2-oxoglutaric acid lithium salt DL-KHG Li

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1187-99-1 SDS

1187-99-1Relevant articles and documents

Stereoselective synthesis of γ-hydroxy-α-amino acids through aldolase-transaminase recycling cascades

Guérard-Hélaine, Christine,Heuson, Egon,Ndiaye, Moussa,Gourbeyre, Léa,Lemaire, Marielle,Hélaine, Virgil,Charmantray, Franck,Petit, Jean-Louis,Salanoubat, Marcel,De Berardinis, Véronique,Gefflaut, Thierry

supporting information, p. 5465 - 5468 (2017/07/06)

Efficient bi-enzymatic cascades combining aldolases and α-transaminases were designed for the synthesis of γ-hydroxy-α-amino acids. These recycling cascades provide high stereoselectivity, atom economy, and an equilibrium shift of the transamination. l-syn or anti-4-hydroxyglutamic acid and d-anti-4,5-dihydroxynorvaline were thus prepared in 83-95% yield in one step from simple substrates.

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