1187551-28-5Relevant articles and documents
Total synthesis of grassystatin A, a probe for cathepsin e function
Yang, Siming,Zhang, Wei,Ding, Ning,Lo, Jeannette,Liu, Yanxia,Clare-Salzler, Michael J.,Luesch, Hendrik,Li, Yingxia
, p. 4774 - 4780 (2012/09/08)
The linear depsipeptide grassystatin A, a valuable probe for the study of cathepsin E function, has been synthesized by a [4+6] strategy. It exhibited specific inhibitory activity against cathepsin E with an IC50 value of 0.8 nM. Our studies in