1190-69-8

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 76, p. 3599, 1954 DOI: 10.1021/ja01642a080

InChI:InChI=1/C8H15NO3/c1-2-12-8(11)6-4-3-5-7(9)10/h2-6H2,1H3,(H2,9,10)

Upstream product

• 64-17-5 ethanol 
• 334-25-8 6-amino-6-oxohexanoic acid 
• 3633-17-8 ethyl 6-aminocaproate hydrochloride 
• 814-49-3 diethyl chlorophosphate 
• 75-03-6 ethyl iodide 
• 38104-99-3 ethyl 1-nitroso-2-oxocyclohexanecarboxylate 
• 141-52-6 sodium ethanolate 
• 1071-71-2 ethyl 6-chloro-6-oxohexanoate 

Downstream Products

• 626-86-8 adipinic acid monoethyl ester 
• 1071-71-2 ethyl 6-chloro-6-oxohexanoate 
• 4450-39-9 ethyl 5-cyanovalerate 

Relevant academic research and scientific papers

Synthesis of some monothienylalkyl esters of aliphatic dicarboxylic acids

1. A. new method was developed for the synthesis of the half-esters of dicarboxylic acids. 2. Some members of the acid esters of acidophobic alcohols were synthesized, and specifically the mono-3-(2-thienyl)propyl ester of adipic acid and the mono-2-(2-thienyl)ethyl ester of pimelic acid.

HYDROLYSIS IN THE ABSENCE OF BULK WATER 1. CHEMOSELECTIVE HYDROLYSIS OF AMIDES USING TETRAHALOPHTALIC ANHYDRIDES

The reaction of primary and secondary amides with tetrafluorophthalic or tetrachlorophtalic anhydride gives carboxylic acids in good yield.The reaction is chemoselective in that the amide functionality can be hydrolyzed in the presence of ester groups.

Antibacterially active amides

Carboxylic acid amides of formula (II): STR1 where R1 and R2 represent a variety of hydrocarbon or heterocyclic groups, possess antibacterial activity and antimycoplasmal activity and are therefore of value in the treatment of human and veterinary bacterial and mycoplasmal infections.