1190930-34-7Relevant academic research and scientific papers
Enantio- and diastereoselective synthesis of syn -β-hydroxy-α- vinyl carboxylic esters via reductive aldol reactions of ethyl allenecarboxylate with 10-tms-9-borabicyclo[3.3.2]decane and DFT analysis of the hydroboration pathway
Kister, Jeremy,Ess, Daniel H.,Roush, William R.
, p. 5436 - 5439 (2013)
An enantio- and diastereoselective synthesis of syn-β-hydroxy-α- vinyl carboxylate esters 3 via the reductive aldol reaction of ethyl allenecarboxylate (2) with 10-trimethylsilyl-9-borabicyclo[3.3.2]decane (1R) has been developed. Density functional theor
The dienolate aldol reaction of (E)-N-crotonoyl C(4)-isopropyl SuperQuat: asymmetric synthesis of α-vinyl-β-hydroxycarboxylic acid derivatives and conversion to α-ethylidene-β-hydroxyesters (β-substituted Baylis-Hillman products)
Davies, Stephen G.,Elend, Dirk L.,Jones, Simon,Roberts, Paul M.,Savory, Edward D.,Smith, Andrew D.,Thomson, James E.
experimental part, p. 7837 - 7851 (2009/12/09)
The synthesis of α-vinyl-β-hydroxyesters and α-ethylidene-β-hydroxyesters (β-substituted Baylis-Hillman products) via the dienolate aldol reaction of (E)-N-crotonoyl C(4)-isopropyl SuperQuat is described. High levels of syn-diastereoselectivity (up to >98
