119830-49-8Relevant academic research and scientific papers
Rhenium-Catalyzed Dehydrogenative Coupling of Alcohols and Amines to Afford Nitrogen-Containing Aromatics and More
Mastalir, Matthias,Glatz, Mathias,Pittenauer, Ernst,Allmaier, Günter,Kirchner, Karl
, p. 1116 - 1120 (2019)
An efficient synthesis of quinolines, pyrimidines, quinoxalines, pyrroles, and aminomethylated aromatic compounds catalyzed by a well-defined Re(I) PNP pincer complex is described. All reactions proceed with liberation of dihydrogen and elimination of water. Under optimized reaction conditions a wide range of organic functional groups are tolerated. This study demonstrates that rhenium catalysts are performing extremely well in dehydrogenative processes with considerably lower catalyst loadings and shorter reaction times when compared to analogous Mn(I) complexes.
Studies on the amino-heck reactions of unsaturated ketones o-phosphinyloximes for the preparation of substituted pyridines
Zhu, Jia-Liang,Su, Yi-Lin,Chan, Yu-Hui,Chen, I-Chia,Liao, Chuan-Chen
experimental part, p. 369 - 387 (2009/06/08)
The amino-Heck cyclization process has been applied into a range of γ,δ-unsaturated ketone O-diethylphosphinyloximes 1 and δ,ε-unsaturated ketone O-diethylphosphinyloximes 7. Under the specific catalytic conditions developed by us, these substrates were found to preferentially undergo the 6-endo cyclization to give the formation of 2-substituted pyridines 3 and substituted methylpyridines 8, respectively, in moderate to good yields. Besides, several interesting aspects on the effects of phosphinyl groups, solvents, bases and molecular sieves on the regioselectivity of the cyclization of 1 have also been realized.
