1202634-22-7

Basic information

• Product Name: 2,2,2-trichloroethyl (3-(tert-butyl)-1-(4-nitrophenyl)-1H-pyrazol-5-yl)carbamate
• Synonyms: 2,2,2-trichloroethyl (3-(tert-butyl)-1-(4-nitrophenyl)-1H-pyrazol-5-yl)carbamate
• CAS NO: 1202634-22-7
• Molecular Weight: 435.694
• Mol File: 1202634-22-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,2,2-trichloroethyl (3-(tert-butyl)-1-(4-nitrophenyl)-1H-pyrazol-5-yl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-trichloroethyl (3-(tert-butyl)-1-(4-nitrophenyl)-1H-pyrazol-5-yl)carbamate(1202634-22-7)
• EPA Substance Registry System: 2,2,2-trichloroethyl (3-(tert-butyl)-1-(4-nitrophenyl)-1H-pyrazol-5-yl)carbamate(1202634-22-7)

Safety Data

• Hazardous Substances Data: 1202634-22-7(Hazardous Substances Data)

Upstream product

• 251658-55-6 3-(tert-butyl)-1-(4-nitrophenyl)-1H-pyrazol-5-amine 
• 17341-93-4 2,2,2-Trichloroethyl chloroformate 
• 59997-51-2 trimethylacetylacetonitrile 
• 636-99-7 4-nitrophenylhydrazine hydrochloride 

Downstream Products

• 1071964-53-8 1-(3-tert-butyl-1-(4-nitrophenyl)-1H-pyrazol-5-yl)-3-(5-(2-morpholinoethoxy)-2H-chromen-8-yl)urea 

Relevant articles and documents

Design, synthesis and biological evaluation of novel substituted N,N′-diaryl ureas as potent p38 inhibitors

A novel series of substituted N,N′-diaryl ureas that act as p38α inhibitors have been designed and synthesized based on two key residues (Gly110 and Thr106) that are different in p38α MAPK than in other kinases. Preliminary biological evaluation indicated

Short Synthesis of 1-(3-tert-Butyl-1-phenyl-1H-pyrazol-5-yl)-3-(5-(2- morpholinoethoxy)-2H-chromen-8-yl) urea derivatives

A short and efficient synthesis of 1-(3-tert-butyl-1-phenyl-1H-pyrazol-5- yl)-3-(5-(2-morpholinoethoxy)-2H-chromen-8-yl) urea derivatives (1a-c), a novel type of p38 MAPK inhibitors, is described. The Claisen thermal rearrangement of arylpropargyl ethers