611-03-0

Basic information

• Product Name: 2,4-DIAMINOBENZOIC ACID DIHYDROCHLORIDE
• Synonyms: 2,4-DIAMINOBENZOIC ACID DIHYDROCHLORIDE;2,4-bis(azanyl)benzoic acid
• CAS NO: 611-03-0
• Molecular Formula: C₇H₈N₂O₂
• Molecular Weight: 225.07
• Mol File: 611-03-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 140°C
• Boiling Point: 274.61°C (rough estimate)
• Flash Point: 196.7°C
• Appearance: /
• Density: 1.2804 (rough estimate)
• Vapor Pressure: 3.61E-07mmHg at 25°C
• Refractive Index: 1.5200 (estimate)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 5.60±0.10(Predicted)
• CAS DataBase Reference: 2,4-DIAMINOBENZOIC ACID DIHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIAMINOBENZOIC ACID DIHYDROCHLORIDE(611-03-0)
• EPA Substance Registry System: 2,4-DIAMINOBENZOIC ACID DIHYDROCHLORIDE(611-03-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 611-03-0(Hazardous Substances Data)

Usage

Uses

2,4-Diaminobenzoic Acid is a reagent used in the optimization of quinazolinones acting as anti-tubercular agents. Also used in the preparation of DNA Polymerase III inhibitors.

InChI:InChI=1/C7H8N2O2/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3H,8-9H2,(H,10,11)

Upstream product

• 5466-84-2 4-nitrophthalic anhydride 
• 610-27-5 4-nitrophthalic acid 
• 85-44-9 phthalic anhydride 
• 95-80-7 4-methylbenzene-1,3-diamine 
• 6282-12-8 2,4-diacetylaminotoluene 
• 1204-29-1 1-ethyl-2,4-dinitrobenzene 
• 619-17-0 4-Nitroanthranilic acid 
• 73748-78-4 2,4-diacetylaminobenzoic acid 

Downstream Products

• 1606159-00-5 C₈H₇N₃OS 
• 81115-53-9 2-acetylamido-4-methyl-5-nitrobenzoic acid 
• 59674-85-0 7-aminoquinazoline-2,4(1H,3H)-dione 
• 619-17-0 4-Nitroanthranilic acid 
• 100076-14-0 7-amino-2-isopropylamino-4H-3,1-benzoxazin-4-one 
• 50-84-0 2,4 dichlorobenzoic acid 

Relevant articles and documents

Synthesis method of 2,4-diaminobenzoic acid

The present invention discloses a synthesis method of 2,4-diaminobenzoic acid, and belongs to the field of chemical synthesis. The synthesis method comprises the following steps: using phthalic anhydride as a raw material; adding concentrated sulfuric acid and fuming nitric acid to generate 4-nitrophthalic acid; adding acetic anhydride into the 4-nitrophthalic acid and heating until the solid is completely dissolved; washing ether to obtain 4-nitro phthalic anhydride; mixing and heating the 4-nitro phthalic anhydride with urea; evacuating a reaction system; then adding hydrochloric acid to obtain 4-nitro-2-formyl acetaminobenzoic acid; obtaining 2-amino-4-nitrobenzoic acid under the conditions of a sodium hypochlorite solution and an ice bath; and finally refluxing with absolute ethanol, and adding an ammonium sulfide solution to finally produce 2,4-diaminobenzoic acid by using microwave heating and other conditions.

One step hair coloring compositions using salts

A hair coloring composition comprising the following two compositions which are mixed just prior to application to the hair: (a) a composition comprising a water-soluble peroxygen oxidizing agent; and (b) a composition comprising one or more oxidative hair coloring agents selected from the group consisting of an aromatic diamine, an amino phenol, a naphthol, a polyhydric phenol, a catechol and mixtures thereof; wherein the composition comprising one or more oxidative hair coloring agents further comprises al least one water soluble carbonate releasing salts; and optionally a water soluble ammonium salt, is described.

Transition metal complexes as dye forming catalysts in hair coloring compositions

A hair coloring composition comprising a first composition which comprises: (a) a dye forming transition metal salt or complex; which is first applied to the hair; and a second composition which comprises the following two compositions which are mixed just prior to application to the hair: (a) a composition comprising a water-soluble peroxygen oxidizing agent; and (b) a composition comprising one or more oxidative hair coloring agents selected from the group consisting of an aromatic diamine, an aminophenol, a polyhydric phenol a catechol and mixtures thereof.