1204677-76-8Relevant academic research and scientific papers
Synthesis of alcohols from m-fluorophenylsulfones and dialkylboranes: Application to the C14-C35 building block of E7389
Liu, Lei,Henderson, James A.,Yamamoto, Akihiko,Bremond, Paul,Kishi, Yoshito
experimental part, p. 2262 - 2265 (2012/06/30)
The reaction of m-fluorophenylsulfone anions with dialkylboranes, followed by alkaline hydroperoxide oxidation, yields alcohols in high yields. Optimization of the process, scope and limitation, and application to the synthesis of one of the C14-C35 building blocks of E7389, a right half analogue of halichondrin B, are reported.
Iodine-mediated thioetherification of alcohols with disulfides or NaSh under microwave irradiation
Hu, Bolun,Sun, Leilei,Tang, Riyuan,Hu, Huanan
, p. 2556 - 2562,7 (2020/09/16)
An efficient and novel method for the thioetherification of an alcohol with disulfides or NaSH under microwave irradiation is presented. In the presence of iodine, a variety of alcohols were smoothly S-alkylated with disulfides or NaSH to give the corresponding thioethers in moderate to excellent yields. Copyright
Regioselective C-S bond formation accomplished by copper-catalyzed regioselective C-F substitution of perfluoroarenes with aryl thioacetates or benzyl thioacetate
Zhou, Qizhong,Zhang, Bin,Du, Tieqi,Gu, Haining,Jiang, Huajiang,Chen, Rener
experimental part, p. 4233 - 4241 (2012/07/14)
Practical and straightforward method for regioselective C-S bond formation accomplished by copper-catalyzed regioselective C-F substitution of electron-deficient perfluoroarenes with aryl thioacetates or benzyl thioacetate has been developed. Because of its high reaction efficiency, good chemoselectivity and regioselectivity, and excellent functional-group compatibility, this protocol provides a useful and operationally simple access to polyfluoroaryl thioethers used for drugs and material chemistry.
A novel and efficient cross-coupling of tris(fluorinated phenyl)boroxins with disulfides catalyzed by CuI/1,10-phenanthroline
Yu, Chuanming,Jin, Beibei,Liu, Zhenyu,Zhong, Weihui
experimental part, p. 485 - 491 (2010/09/17)
Under an oxygen atmosphere, the cross-coupling of tris(fluorinated phenyl)boroxins and disulfides catalyzed by CuI/1,10-phenanthroline were smoothly achieved to produce the corresponding asymmetric fluorinated arylsulfides in good-to-excellent yields.
Synthesis of aryl benzyl NH-sulfoximines
Barry, Nicola,Brondel, Nicolas,Lawrence, Simon E.,Maguire, Anita R.
experimental part, p. 10660 - 10670 (2010/01/16)
Efficient synthesis and characterisation of a series of aryl benzyl NH-sulfoximines are described. While N-protected versions of aryl benzyl sulfoximines have been previously described, reports of their deprotection are very limited, presumably due to lab
