1206800-18-1 Usage
General Description
The chemical 1H-Indazol-5-ol, 6-bromo- is a compound with the molecular formula C7H5BrN2O. It is a derivative of indazole, a heterocyclic aromatic organic compound. This particular compound contains a bromine atom at the 6-position of the indazole ring, with a hydroxyl group at the 5-position. While the specific properties and uses of this compound may vary, indazoles and their derivatives are known for their potential applications in pharmaceuticals, agrochemicals, and materials science. Further research and testing may be required to fully understand the properties and potential uses of 1H-Indazol-5-ol, 6-bromo- in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 1206800-18-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,6,8,0 and 0 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1206800-18:
(9*1)+(8*2)+(7*0)+(6*6)+(5*8)+(4*0)+(3*0)+(2*1)+(1*8)=111
111 % 10 = 1
So 1206800-18-1 is a valid CAS Registry Number.
1206800-18-1Relevant articles and documents
Route design and development of a MET kinase inhibitor: A copper-catalyzed preparation of an N 1 - Methylindazole
Kallman, Neil J.,Liu, Chin,Yates, Matthew H.,Linder, Ryan J.,Ruble, J. Craig,Kogut, Eugene F.,Patterson, Lawrence E.,Laird, Dana L. T.,Hansen, Marvin M.
, p. 501 - 510 (2014/05/06)
The synthesis of a MET kinase inhibitor in an overall yield of 22% was achieved over eight steps starting with 3-hydroxybenzaldehyde, an improvement from the initial 12-step process with a 5.4% yield. Highlights of the process chemistry design and development are a Cu-catalyzed cyclization to form an important N1-methylindazole ring, a selective nitro reduction in the presence of an aryl bromide, a late-stage Suzuki cross-coupling, and a base-promoted Boc deprotection to form the desired drug candidate.
