1206800-56-7

Basic information

• Product Name: tert-butyl 4-(5-(4-amino-2-fluorophenoxy)-1-methyl-1H-indazol-6-yl)-1H-pyrazole-1-carboxylate
• Synonyms: tert-butyl 4-(5-(4-amino-2-fluorophenoxy)-1-methyl-1H-indazol-6-yl)-1H-pyrazole-1-carboxylate
• CAS NO: 1206800-56-7
• Molecular Weight: 423.447
• Mol File: 1206800-56-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-(5-(4-amino-2-fluorophenoxy)-1-methyl-1H-indazol-6-yl)-1H-pyrazole-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(5-(4-amino-2-fluorophenoxy)-1-methyl-1H-indazol-6-yl)-1H-pyrazole-1-carboxylate(1206800-56-7)
• EPA Substance Registry System: tert-butyl 4-(5-(4-amino-2-fluorophenoxy)-1-methyl-1H-indazol-6-yl)-1H-pyrazole-1-carboxylate(1206800-56-7)

Safety Data

• Hazardous Substances Data: 1206800-56-7(Hazardous Substances Data)

Upstream product

• 552846-17-0 tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole-1-carboxylate 
• 1206800-28-3 6-bromo-5-(2-fluoro-4-nitrophenoxy)-2-(tetrahydro-2H-pyran-2-yl)-2H-indazole 
• 1206800-27-2 6-bromo-2-(tetrahydro-2H-pyran-2-yl)-2H-indazol-5-ol 
• 1206800-25-0 2,4-dibromo-5-(2-fluoro-4-nitrophenoxy) benzaldehyde 
• 1206800-18-1 6-bromo-1H-indazol-5-ol 
• 1206800-17-0 6-bromo-5-methoxy-1H-indazole 
• 1206800-26-1 1-(2,4-dibromo-5-(2-fluoro-4-nitrophenoxy)benzylidene)-2-methylhydrazine 
• 1577180-04-1 C₉H₁₀Br₂N₂O 
• 861084-04-0 5-bromo-4-methoxy-2-methylbenzenamine 
• 31601-41-9 N-(4-methoxy-2-methylphenyl)acetamide 
• 1206800-24-9 6-bromo-5-(2-fluoro-4-nitrophenoxy)-1-methyl-1H-indazole 
• 102-50-1 2-methyl-4-methoxyaniline 
• 3111-51-1 2,4-dibromo-5-hydroxybenzaldehyde 
• 100-83-4 meta-hydroxybenzaldehyde 

Downstream Products

• 1206801-36-6 tert-butyl 4-(5-(2-fluoro-4-(1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamido)phenoxy)-1-methyl-1H-indazol-6-yl)-1H-pyrazole-1-carboxylate 
• 1206799-15-6 N-(3-fluoro-4-((1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl)oxy)phenyl)-1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide 
• 1206800-67-0 3-fluoro-4-(1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yloxy)aniline 

Relevant articles and documents

TRK INHIBITOR AS ANTI-CANCER DRUG

The present disclosure relates to a group of tropomyosin receptor kinase inhibitors comprising an amido-phenoxy-indazole structure fragment. These compounds show potent inhibitory effects on various oncogenic kinases, especially TRK, and thus can be used

AMIDOPHENOXYINDAZOLES USEFUL AS INHIBITORS OF C-MET

The present invention provides amidophenoxyindazole compounds useful in the treatment of cancer.