120980-33-8

Upstream product

• 480-39-7 pinocembrin 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 
• 18065-05-9 1-[2,4-bis(benzyloxy)-6-hydroxyphenyl]ethanone 
• 69389-64-6 2',4'-dibenzyloxy-6'-hydroxychalcone 
• 100-52-7 benzaldehyde 
• 480-40-0 5,7-dihydroxy-2-phenyl-chromen-4-one 

Downstream Products

• 1159852-71-7 C₃₀H₂₇NO₃ 
• 1159852-69-3 C₃₀H₂₇NO₃ 
• 1209470-08-5 6-benzyl-5,7-dihydroxyflavanone 
• 1209470-07-4 8-benzyl-5,7-dihydroxyflavanone 
• 480-39-7 pinocembrin 
• 206660-42-6 (R)-5,7-dihydroxyflavanone 
• 1159852-73-9 C₂₂H₁₈O₄ 
• 1159852-74-0 C₂₂H₁₈O₄ 

Relevant academic research and scientific papers

Bioactive Formylated Flavonoids from Eugenia rigida: Isolation, Synthesis, and X-ray Crystallography

Two new flavonoids, rac-6-formyl-5,7-dihydroxyflavanone (1) and 2′,6′-dihydroxy-4′-methoxy-3′-methylchalcone (2), together with five known derivatives, rac-8-formyl-5,7-dihydroxyflavanone (3), 4′,6′-dihydroxy-2′-methoxy-3′-methyldihydrochalcone (4), rac-7-hydroxy-5-methoxy-6-methylflavanone (5), 3′-formyl-2′,4′,6′-trihydroxy-5′-methyldihydrochalcone (6), and 3′-formyl-2′,4′,6′-trihydroxydihydrochalcone (7), were isolated from the leaves of Eugenia rigida. The individual (S)- and (R)-enantiomers of 1 and 3, together with the corresponding formylated flavones 8 (6-formyl-5,7-dihydroxyflavone) and 9 (8-formyl-5,7-dihydroxyflavone), as well as 2′,4′,6′-trihydroxychalcone (10), 3′-formyl-2′,4′,6′-trihydroxychalcone (11), and the corresponding 3′-formyl-2′,4′,6′-trihydroxydihydrochalcone (7) and 2′,4′,6′-trihydroxydihydrochalcone (12), were synthesized. The structures of the isolated and synthetic compounds were established via NMR, HRESIMS, and electronic circular dichroism data. In addition, the structures of 3, 5, and 8 were confirmed by single-crystal X-ray diffraction crystallography. The isolated and synthetic flavonoids were evaluated for their antimicrobial and cytotoxic activities against a panel of microorganisms and solid tumor cell lines.

METHOD FOR RESOLUTION OF A MIXTURE OF PINOCEMBRIN OPTICAL ISOMERS, ESPECIALLY A PINOCEMBRIN RACEMATE

The present invention relates to a method for resolution of a mixture of pinocembrin optical isomers, in particular a pinocembrin racemate, using a chiral primary amine or a chiral sulfinamide. The present invention also relates to a (R)-(+)-pinocembrin obtained by the method.

Acidic rearrangement of (benzyloxy)chalcones: A short synthesis of chamanetin

Treatment of (benzyloxy)chalcones with trifluoroacetic acid in refluxing chloroform gave several new benzyl(hydroxy)flavanones in high yields and good regioselectivities. By using this procedure, we prepared the natural compound chamanetin in good yield from readily available reagents. Georg Thieme Verlag Stuttgart - New York.