1211533-93-5

Basic information

• Product Name: 5-Chloro-2-methyl-3-nitropyridine
• Synonyms: 5-Chloro-2-methyl-3-nitropyridine;5-Chloro-2-Methyl-3-nitro...;Pyridine, 5-chloro-2-methyl-3-nitro-
• CAS NO: 1211533-93-5
• Molecular Formula: C6H5ClN2O2
• Molecular Weight: 172.5691
• Mol File: 1211533-93-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 230℃
• Flash Point: 93℃
• Appearance: /
• Density: 1.406
• Storage Temp.: Room temperature.
• PKA: -0.37±0.20(Predicted)
• CAS DataBase Reference: 5-Chloro-2-methyl-3-nitropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloro-2-methyl-3-nitropyridine(1211533-93-5)
• EPA Substance Registry System: 5-Chloro-2-methyl-3-nitropyridine(1211533-93-5)

Safety Data

• Hazardous Substances Data: 1211533-93-5(Hazardous Substances Data)

Usage

General Description

5-Chloro-2-methyl-3-nitropyridine is a chemical compound with the molecular formula C6H5ClN2O2. It is a yellow crystalline solid with a molecular weight of 172.57 g/mol. 5-Chloro-2-methyl-3-nitropyridine is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used in the production of dyes and pigments. The presence of a nitro group and a chlorine atom in its structure makes 5-Chloro-2-methyl-3-nitropyridine a versatile building block for the synthesis of various organic compounds. However, it is important to handle this chemical with caution due to its potential hazardous nature.

Upstream product

• 136888-13-6 diethyl (5-chloro-3-nitropyridin-2-yl )propanedioate 
• 21427-62-3 2,5-dichloro-3-nitropyridine 
• 105-53-3 diethyl malonate 

Downstream Products

• 1404456-53-6 GSK2830371 
• 89639-36-1 5-chloro-2-methylpyridin-3-amine 
• 1404456-63-8 5-{[(5-chloro-2-methyl-3-pyridinyl)amino]methyl}-2-thiophenecarboxylic acid 
• 1404456-26-3 (S)-5-{[(5-chloro-2-methylpyridin-3-yl)amino]methyl}-N-{3-cyclohexyl-1-[(2-hydroxyethyl)amino]-1-oxopropan-2-yl}thiophene-2-carboxamide 
• 1404456-47-8 (S)-5-{[(5-chloro-2-methylpyridin-3-yl)oxy]methyl}-N-{3-cyclohexyl-1-[(2-hydroxyethyl)amino]-1-oxopropan-2-yl}thiophene-2-carboxamide 
• 89943-02-2 2,5-dimethyl-3-aminopyridine 
• 17117-19-0 2,5-dimethyl-3-bromopyridine 
• 52381-06-3 2,5-dimethyl-3-nitropyridine 

Relevant articles and documents

3-OXAZOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF

The present invention relates to a novel 3-indazolinone compound that regulates or inhibits the activity of indoleamine 2,3-dioxygenase (IDO), the method for the preparation thereof and the use thereof in medicine. In particular, the present invention relates to a compound represented by the general formula (I) and a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the compound or a pharmaceutically acceptable salt thereof, a method for treating or preventing IDO-mediated diseases, especially tumors, by use of the compound or a pharmaceutically acceptable salt thereof, and a method for preparing the compound or a pharmaceutically acceptable salt thereof. The present invention further relates to use of the compound or a pharmaceutically acceptable salt thereof or a composition comprising the compound or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for treating or preventing IDO-mediated diseases, especially tumors.Wherein the substituents of the general formula (I) are defined the same as that in the specification.