1211533-93-5

Usage

Uses

Used in Pharmaceutical Synthesis:
5-Chloro-2-methyl-3-nitropyridine is utilized as an intermediate in the synthesis of pharmaceuticals, playing a crucial role in the development of new drugs. Its unique structure allows for the creation of a wide range of medicinal compounds.
Used in Agrochemical Production:
In the agrochemical industry, 5-Chloro-2-methyl-3-nitropyridine serves as an intermediate, contributing to the formulation of various agricultural chemicals that help protect crops and enhance their growth.
Used in Dye and Pigment Manufacturing:
5-Chloro-2-methyl-3-nitropyridine is also employed in the production of dyes and pigments, where its chemical properties are leveraged to create a diverse array of colorants for various applications.
Used in Organic Synthesis:
As a versatile building block, 5-Chloro-2-methyl-3-nitropyridine is used in organic synthesis for the preparation of different organic compounds, showcasing its broad applicability in chemical research and industry.

Upstream product

• 136888-13-6 diethyl (5-chloro-3-nitropyridin-2-yl )propanedioate 
• 21427-62-3 2,5-dichloro-3-nitropyridine 
• 105-53-3 diethyl malonate 

Downstream Products

• 1404456-53-6 GSK2830371 
• 89639-36-1 5-chloro-2-methylpyridin-3-amine 
• 1404456-63-8 5-{[(5-chloro-2-methyl-3-pyridinyl)amino]methyl}-2-thiophenecarboxylic acid 
• 1404456-26-3 (S)-5-{[(5-chloro-2-methylpyridin-3-yl)amino]methyl}-N-{3-cyclohexyl-1-[(2-hydroxyethyl)amino]-1-oxopropan-2-yl}thiophene-2-carboxamide 
• 1404456-47-8 (S)-5-{[(5-chloro-2-methylpyridin-3-yl)oxy]methyl}-N-{3-cyclohexyl-1-[(2-hydroxyethyl)amino]-1-oxopropan-2-yl}thiophene-2-carboxamide 
• 89943-02-2 2,5-dimethyl-3-aminopyridine 
• 17117-19-0 2,5-dimethyl-3-bromopyridine 
• 52381-06-3 2,5-dimethyl-3-nitropyridine 

Relevant academic research and scientific papers

3-OXAZOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF

The present invention relates to a novel 3-indazolinone compound that regulates or inhibits the activity of indoleamine 2,3-dioxygenase (IDO), the method for the preparation thereof and the use thereof in medicine. In particular, the present invention relates to a compound represented by the general formula (I) and a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the compound or a pharmaceutically acceptable salt thereof, a method for treating or preventing IDO-mediated diseases, especially tumors, by use of the compound or a pharmaceutically acceptable salt thereof, and a method for preparing the compound or a pharmaceutically acceptable salt thereof. The present invention further relates to use of the compound or a pharmaceutically acceptable salt thereof or a composition comprising the compound or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for treating or preventing IDO-mediated diseases, especially tumors.Wherein the substituents of the general formula (I) are defined the same as that in the specification.

NOVEL COMPOUNDS AS WIP1 INHIBITORS

This invention relates to the use of acylated alanine derivatives for the modulation, notably the inhibition of the activity of WIP1. Suitably, the present invention relates to the use of acylated alanine derivatives in the treatment of cancer.