89639-36-1

Usage

Uses

Used in Pharmaceutical Synthesis:
3-Amino-5-chloropicoline is utilized as a key intermediate in the production of various pharmaceuticals. Its presence in the molecular structure allows for the development of new drugs with specific therapeutic properties, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Production:
In the agrochemical industry, 3-Amino-5-chloropicoline serves as a building block for the creation of pesticides and other crop protection agents. Its incorporation into these compounds can enhance their effectiveness in protecting crops from pests and diseases, thereby supporting agricultural productivity.
Used as a Catalyst in Organic Reactions:
3-Amino-5-chloropicoline has been studied for its potential as a catalyst in various organic reactions. Its unique chemical properties enable it to facilitate and accelerate chemical processes, making it a promising candidate for improving the efficiency and selectivity of synthetic pathways in organic chemistry.

Upstream product

• 78607-32-6 3-amino-2,5-dichloropyridine 
• 13061-96-6 dihydroxy-methyl-borane 
• 1211533-93-5 2-methyl-3-nitro-5-chloropyridine 
• 21427-62-3 2,5-dichloro-3-nitropyridine 

Downstream Products

• 1404456-53-6 GSK2830371 
• 1404456-63-8 5-{[(5-chloro-2-methyl-3-pyridinyl)amino]methyl}-2-thiophenecarboxylic acid 
• 1404456-26-3 (S)-5-{[(5-chloro-2-methylpyridin-3-yl)amino]methyl}-N-{3-cyclohexyl-1-[(2-hydroxyethyl)amino]-1-oxopropan-2-yl}thiophene-2-carboxamide 
• 1404456-47-8 (S)-5-{[(5-chloro-2-methylpyridin-3-yl)oxy]methyl}-N-{3-cyclohexyl-1-[(2-hydroxyethyl)amino]-1-oxopropan-2-yl}thiophene-2-carboxamide 

Relevant academic research and scientific papers

AZAINDOLE CARBOXAMIDE COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS

Provided herein are compounds of Formula (I) and Formula (II): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of tuberculosis.

(PYRIDIN-2-YL)AMINE DERIVATIVES AS TGF-BETA R1 (ALK5) INHIBITORS FOR THE TREATMENT OF CANCER

The present invention relates to pharmaceutical compounds, compositions and methods, especially as they are related to compositions and methods for the treatment and/or prevention of a proliferation disorder associated with ΤGFβR1 activity, such as a cancer or fibrosis. The invention provides compounds of Formula (I) and Formula (II) as further described herein having an acidic moiety that enhances tissue specificity for targeted tissues and organs. The invention includes pharmaceutical compositions, pharmaceutical combinations, and methods of use of these compounds for treating conditions including cancer or fibrosis.

NOVEL COMPOUNDS AS WIP1 INHIBITORS

This invention relates to the use of acylated alanine derivatives for the modulation, notably the inhibition of the activity of WIP1. Suitably, the present invention relates to the use of acylated alanine derivatives in the treatment of cancer.